User profiles for Maia A. Smith

Maia A Smith

University of British Columbia
Verified email at sfu.ca
Cited by 2233

The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates

…, S Žentelis, KR Jepson, R Goya, MA Smith… - Science translational …, 2021 - science.org
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) poses a public health threat
for which preventive and therapeutic agents are urgently needed. Neutralizing antibodies …

[PDF][PDF] LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants

…, NL Kallewaard, K Jepson, R Goya, MA Smith… - Cell reports, 2022 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-neutralizing monoclonal
antibodies (mAbs) can reduce the risk of hospitalization from coronavirus disease 2019 (…

Divergent modes of clonal spread and intraperitoneal mixing in high-grade serous ovarian cancer

…, D Yap, A Wan, LM Prentice, J Khattra, MA Smith… - Nature …, 2016 - nature.com
We performed phylogenetic analysis of high-grade serous ovarian cancers (68 samples from
seven patients), identifying constituent clones and quantifying their relative abundances at …

[PDF][PDF] Interfaces of malignant and immunologic clonal dynamics in ovarian cancer

…, DR Cochrane, JLP Lim, W Yang, A Roth, MA Smith… - Cell, 2018 - cell.com
High-grade serous ovarian cancer (HGSC) exhibits extensive malignant clonal diversity with
widespread but non-random patterns of disease dissemination. We investigated whether …

[HTML][HTML] Histological transformation and progression in follicular lymphoma: a clonal evolution study

…, D Yap, S Ben-Neriah, J Rosner, MA Smith… - PLoS …, 2016 - journals.plos.org
Background Follicular lymphoma (FL) is an indolent, yet incurable B cell malignancy. A subset
of patients experience an increased mortality rate driven by two distinct clinical end points…

LY-CoV555, a rapidly isolated potent neutralizing antibody, provides protection in a non-human primate model of SARS-CoV-2 infection

…, Y Hwang, S Žentelis, KR Jepson, R Goya, MA Smith… - BioRxiv, 2020 - biorxiv.org
SARS-CoV-2 poses a public health threat for which therapeutic agents are urgently needed.
Herein, we report that high-throughput microfluidic screening of antigen-specific B-cells led …

Clonal genotype and population structure inference from single-cell tumor sequencing

…, E Laks, J Biele, D Yap, A Wan, MA Smith… - Nature …, 2016 - nature.com
Single-cell DNA sequencing has great potential to reveal the clonal genotypes and population
structure of human cancers. However, single-cell data suffer from missing values and …

[HTML][HTML] Estimating total morbidity burden of COVID-19: relative importance of death and disability

MP Smith - Journal of Clinical Epidemiology, 2022 - Elsevier
Objective Calculations of disease burden of COVID-19, used to allocate scarce resources,
have historically considered only mortality. However, survivors often develop postinfectious ‘…

E-scape: interactive visualization of single-cell phylogenetics and cancer evolution

MA Smith, CB Nielsen, FC Chan, A McPherson… - Nature …, 2017 - nature.com
To the Editor: Populations of cancer cells emerge through branched evolutionary processes
characterized by variable cell fitness and differential growth. Cell population dynamics …

Neighbourhood and physical activity in German adolescents: GINIplus and LISAplus

I Markevych, MP Smith, S Jochner, M Standl… - Environmental …, 2016 - Elsevier
Introduction Impact of neighbourhood on physical activity (PA) is under-investigated in
European adolescents, and few studies have used objective data on both exposures and …