User profiles for Maia A. Smith
Maia A SmithUniversity of British Columbia Verified email at sfu.ca Cited by 2233 |
The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates
…, S Žentelis, KR Jepson, R Goya, MA Smith… - Science translational …, 2021 - science.org
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) poses a public health threat
for which preventive and therapeutic agents are urgently needed. Neutralizing antibodies …
for which preventive and therapeutic agents are urgently needed. Neutralizing antibodies …
[PDF][PDF] LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants
…, NL Kallewaard, K Jepson, R Goya, MA Smith… - Cell reports, 2022 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-neutralizing monoclonal
antibodies (mAbs) can reduce the risk of hospitalization from coronavirus disease 2019 (…
antibodies (mAbs) can reduce the risk of hospitalization from coronavirus disease 2019 (…
Divergent modes of clonal spread and intraperitoneal mixing in high-grade serous ovarian cancer
We performed phylogenetic analysis of high-grade serous ovarian cancers (68 samples from
seven patients), identifying constituent clones and quantifying their relative abundances at …
seven patients), identifying constituent clones and quantifying their relative abundances at …
[PDF][PDF] Interfaces of malignant and immunologic clonal dynamics in ovarian cancer
High-grade serous ovarian cancer (HGSC) exhibits extensive malignant clonal diversity with
widespread but non-random patterns of disease dissemination. We investigated whether …
widespread but non-random patterns of disease dissemination. We investigated whether …
[HTML][HTML] Histological transformation and progression in follicular lymphoma: a clonal evolution study
Background Follicular lymphoma (FL) is an indolent, yet incurable B cell malignancy. A subset
of patients experience an increased mortality rate driven by two distinct clinical end points…
of patients experience an increased mortality rate driven by two distinct clinical end points…
LY-CoV555, a rapidly isolated potent neutralizing antibody, provides protection in a non-human primate model of SARS-CoV-2 infection
…, Y Hwang, S Žentelis, KR Jepson, R Goya, MA Smith… - BioRxiv, 2020 - biorxiv.org
SARS-CoV-2 poses a public health threat for which therapeutic agents are urgently needed.
Herein, we report that high-throughput microfluidic screening of antigen-specific B-cells led …
Herein, we report that high-throughput microfluidic screening of antigen-specific B-cells led …
Clonal genotype and population structure inference from single-cell tumor sequencing
Single-cell DNA sequencing has great potential to reveal the clonal genotypes and population
structure of human cancers. However, single-cell data suffer from missing values and …
structure of human cancers. However, single-cell data suffer from missing values and …
[HTML][HTML] Estimating total morbidity burden of COVID-19: relative importance of death and disability
MP Smith - Journal of Clinical Epidemiology, 2022 - Elsevier
Objective Calculations of disease burden of COVID-19, used to allocate scarce resources,
have historically considered only mortality. However, survivors often develop postinfectious ‘…
have historically considered only mortality. However, survivors often develop postinfectious ‘…
E-scape: interactive visualization of single-cell phylogenetics and cancer evolution
To the Editor: Populations of cancer cells emerge through branched evolutionary processes
characterized by variable cell fitness and differential growth. Cell population dynamics …
characterized by variable cell fitness and differential growth. Cell population dynamics …
Neighbourhood and physical activity in German adolescents: GINIplus and LISAplus
Introduction Impact of neighbourhood on physical activity (PA) is under-investigated in
European adolescents, and few studies have used objective data on both exposures and …
European adolescents, and few studies have used objective data on both exposures and …