Dementia is an increasing focus for policymakers, civil organizations and multidisciplinary
researchers. The most recent descriptive epidemiological research into dementia is enabling …

We aimed to obtain reliable reference charts for sleep duration, estimate the prevalence of
sleep complaints across the lifespan and identify risk indicators of poor sleep. Studies were …

Background and Purpose— Ischemic stroke (IS) and coronary artery disease (CAD) share
several risk factors and each has a substantial heritability. We conducted a genome-wide …

We conducted a meta-analysis of Parkinson's disease genome-wide association studies
using a common set of 7,893,274 variants across 13,708 cases and 95,282 controls. Twenty-six …

Eleven susceptibility loci for late-onset Alzheimer's disease (LOAD) were identified by previous
studies; however, a large portion of the genetic risk for this disease remains unexplained. …

Background Sequence variants, including the ε4 allele of apolipoprotein E, have been
associated with the risk of the common late-onset form of Alzheimer's disease. Few rare variants …

… of Medicine, and Departments of Biostatistics (Drs DeStefano, Beiser, Du, and Farrer) and
Epidemiology (Dr Farrer), Boston University School of Public Health, Boston, Massachusetts; …

Background Magnetic resonance imaging (MRI) of the brain is increasingly used both in
research and in clinical medicine, and scanner hardware and MRI sequences are continually …

We sought to identify new susceptibility loci for Alzheimer's disease through a staged
association study (GERAD+) and by testing suggestive loci reported by the Alzheimer's Disease …

Stroke has multiple etiologies, but the underlying genes and pathways are largely unknown.
We conducted a multiancestry genome-wide-association meta-analysis in 521,612 …