We describe an analysis of genome variation in 825 P. falciparum samples from Asia and
Africa that identifies an unusual pattern of parasite population structure at the epicenter of …

Plasmodium malariae is often reported as a benign malaria parasite. There are limited data
on its biology and disease burden in sub-Saharan Africa (sSA) possibly due to the …

The COVID-19 pandemic is one of the fastest evolving pandemics in recent history. As such,
the SARS-CoV-2 viral evolution needs to be continuously tracked. This study sequenced …

Background Anti-malarial drug resistance remains a key concern for the global fight against
malaria. In Ghana sulfadoxine-pyrimethamine (SP) is used for intermittent preventive …

Understanding genomic variation and population structure of Plasmodium falciparum across
Africa is necessary to sustain progress toward malaria elimination. Genome clustering of …

We report a large multicenter genome-wide association study of Plasmodium falciparum
resistance to artemisinin, the frontline antimalarial drug. Across 15 locations in Southeast Asia, …

Malaria elimination strategies require surveillance of the parasite population for genetic
changes that demand a public health response, such as new forms of drug resistance 1 , 2 . …

Mutations in the Plasmodium falciparum K13-propeller domain have recently been shown
to be important determinants of artemisinin resistance in Southeast Asia. This study …

Plasmodium vivax has been largely neglected over the past century, despite a widespread
recognition of its burden across region where it is endemic. The parasite invades reticulocytes…

Elucidation of the evolutionary history and interrelatedness of Plasmodium species that
infect humans has been hampered by a lack of genetic information for three human-infective …