Colorectal cancer (CRC) rates for Japanese migrants to the United States increased rapidly
to surpass the level of the host population. CRC rates for the Japanese in Hawaii and …

The rapid pace of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2;
COVID-19) pandemic presents challenges to the real-time collection of population-scale data to …

A cancer protective effect from plant-derived foods has been found with uncommon consistency
in epidemiologic studies. However, it has been difficult to identify specific components …

Variation in colorectal cancer rates between countries and within ethnic groups upon
migration and/or Westernization suggests a role for some aspects of Western lifestyle in the …

Microsatellite instability (MSI) occurs in 10% to 20% of colorectal cancers (CRC) and has
been attributed to both MLH1 promoter hypermethylation and germline mutation in the …

Background Lynch syndrome is a highly penetrant cancer predisposition syndrome caused
by germline mutations in DNA mismatch repair (MMR) genes. We estimated the risks of …

The dramatic shift in the pathological presentation of lung cancer [the proportional decrease
in squamous cell carcinoma (SCC) and increase in adenocarcinoma (AC)] observed in the …

Objective: This population-based case–control study was designed to investigate the
interrelationships between polymorphisms in the methylenetetrahydrofolate (MTHFR C677T and …

Numerous studies have associated colorectal adenoma with smoking and large bowel
cancer with consumption of foods potentially containing polycyclic aromatic hydrocarbons. …

Cytochrome P4502E1 (CYP2E1) is considered to play an important role in the metabolic
activation of procarcinogens such as N-nitrosoamines and low molecular weight organic …