[HTML][HTML] From structure to systems: high-resolution, quantitative genetic analysis of RNA polymerase II

…, JJ Benschop, JH Morris, C Qiu, F Hu, LK Tang… - Cell, 2013 - cell.com
RNA polymerase II (RNAPII) lies at the core of dynamic control of gene expression. Using
53 RNAPII point mutants, we generated a point mutant epistatic miniarray profile (pE-MAP) …

Neuropilin 1 balances β8 integrin-activated TGFβ signaling to control sprouting angiogenesis in the brain

S Hirota, TP Clements, LK Tang, JE Morales… - …, 2015 - journals.biologists.com
Angiogenesis in the developing central nervous system (CNS) is regulated by neuroepithelial
cells, although the genes and pathways that couple these cells to blood vessels remain …

PRAISE-HK: A personalized real-time air quality informatics system for citizen participation in exposure and health risk management

…, MS Hossain, KTJ Tang, XQ Lao, R Leung… - Sustainable Cities and …, 2020 - Elsevier
Exposure to air pollutants causes a range of adverse health effects. These harmful effects
occur whenever and wherever people come into direct contact with air pollution. Therefore, …

Factors affecting variability in gaseous and particle microenvironmental air pollutant concentrations in Hong Kong primary and secondary schools

…, P Wei, MS Hossain, TL Hohenberger, KW Leung… - Indoor …, 2021 - Wiley Online Library
School‐age children are particularly susceptible to exposure to air pollutants. To quantify
factors affecting children's exposure at school, indoor and outdoor microenvironmental air …

[HTML][HTML] Ecogeographical adaptation revisited: Morphological variations in the plateau Brown frog along an elevation gradient on the qinghai–Tibetan plateau

KW Leung, S Yang, X Wang, K Tang, J Hu - Biology, 2021 - mdpi.com
Simple Summary A number of studies have explored how the body size and extremities of
frogs vary in response to the changing environmental conditions across different geographical …

[HTML][HTML] High-resolution phenotypic landscape of the RNA polymerase II trigger loop

…, P Cui, H Jin, N Muthukrishnan, LK Tang… - PLoS …, 2016 - journals.plos.org
The active sites of multisubunit RNA polymerases have a “trigger loop” (TL) that multitasks
in substrate selection, catalysis, and translocation. To dissect the Saccharomyces cerevisiae …

Nck deficiency is associated with delayed breast carcinoma progression and reduced metastasis

DC Morris, JL Popp, LK Tang, HC Gibbs… - Molecular biology of …, 2017 - Am Soc Cell Biol
Although it is known that noncatalytic region of tyrosine kinase (Nck) regulates cell adhesion
and migration by bridging tyrosine phosphorylation with cytoskeletal remodeling, the role of …

The cytoskeletal adapter protein spinophilin regulates invadopodia dynamics and tumor cell invasion in glioblastoma

M Cheerathodi, NG Avci, PA Guerrero, LK Tang… - Molecular Cancer …, 2016 - AACR
Glioblastoma is a primary brain cancer that is resistant to all treatment modalities. This
resistance is due, in large part, to invasive cancer cells that disperse from the main tumor site, …

[PDF][PDF] Angiographic factors associated with haemorrhagic presentation of brain arteriovenous malformation in a Chinese paediatric population

…, TW Yeung, YC Wong, KW Leung, JL Khoo, KW Tang - Hong Kong Med J, 2015 - hkmj.org
Objective: To identify specific angiographic factors associated with haemorrhagic presentation
of brain arteriovenous malformation in Chinese paediatric patients. Design: Retrospective …

Single particle tracking analysis of the chloroplast division protein FtsZ anchoring to the inner envelope membrane

CB Johnson, LK Tang, AG Smith… - Microscopy and …, 2013 - academic.oup.com
Replication of chloroplast in plant cells is an essential process that requires co-assembly of
the tubulin-like plastid division proteins FtsZ1 and FtsZ2 at mid-chloroplast to form a ring …