Reactive astrocytes are strongly induced by central nervous system (CNS) injury and disease,
but their role is poorly understood. Here we show that a subtype of reactive astrocytes, …

The rhesus macaque (Macaca mulatta) is an abundant primate species that diverged from
the ancestors of Homo sapiens about 25 million years ago. Because they are genetically and …

Structural variants are implicated in numerous diseases and make up the majority of varying
nucleotides among human genomes. Here we describe an integrated set of eight structural …

The functional and molecular similarities and distinctions between human and murine astrocytes
are poorly understood. Here, we report the development of an immunopanning method …

The human cerebral cortex develops through an elaborate succession of cellular events that,
when disrupted, can lead to neuropsychiatric disease. The ability to reprogram somatic …

To many, periodic mechanical conformational motion of molecules is mesmerizing to a
degree that is difficult to explain rationally: It is almost as hard to stop watching an image of …

To achieve its precise neural connectivity, the developing mammalian nervous system
undergoes extensive activity-dependent synapse remodelling. Recently, microglial cells have …

The decline of cognitive function occurs with aging, but the mechanisms responsible are
unknown. Astrocytes instruct the formation, maturation, and elimination of synapses, and …

Astrocytes are now emerging as key participants in many aspects of brain development,
function and disease. In particular, new evidence shows that astrocytes powerfully control the …

… Laura Clarke , Laura Clarke … Aken, Sarah Ayling, Daniel Barrell, Laura Clarke, Valery
Curwen, Susan Fairley, Julio Fernandez Banet, Konstantinos Billis, Carlos García Girón, Thibaut …