User profiles for Kelvin M. Kimenyi
Kelvin Muteru KimenyiUniversity of Nairobi; KEMRI Wellcome Trust Research Programme Verified email at kemri-wellcome.org Cited by 200 |
[HTML][HTML] A review of the frequencies of Plasmodium falciparum Kelch 13 artemisinin resistance mutations in Africa
Artemisinin resistance (AR) emerged in South East Asia 13 years ago and the identification
of the resistance conferring molecular marker, Plasmodium falciparum Kelch 13 (Pfk13), 7 …
of the resistance conferring molecular marker, Plasmodium falciparum Kelch 13 (Pfk13), 7 …
[HTML][HTML] Understanding P. falciparum asymptomatic infections: a proposition for a transcriptomic approach
Malaria is still a significant public health burden in the tropics. Infection with malaria causing
parasites results in a wide range of clinical disease presentations, from severe to …
parasites results in a wide range of clinical disease presentations, from severe to …
Amplicon Sequencing as a Potential Surveillance Tool for Complexity of Infection and Drug Resistance Markers in Plasmodium falciparum Asymptomatic Infections
K Wamae, KM Kimenyi, V Osoti… - The Journal of …, 2022 - academic.oup.com
Background Genotyping Plasmodium falciparum subpopulations in malaria infections is an
important aspect of malaria molecular epidemiology to understand within-host diversity and …
important aspect of malaria molecular epidemiology to understand within-host diversity and …
[HTML][HTML] Maintenance of high temporal Plasmodium falciparum genetic diversity and complexity of infection in asymptomatic and symptomatic infections in Kilifi …
KM Kimenyi, K Wamae, JM Ngoi, ZR de Laurent… - Malaria Journal, 2022 - Springer
Background High levels of genetic diversity are common characteristics of Plasmodium
falciparum parasite populations in high malaria transmission regions. There has been a decline …
falciparum parasite populations in high malaria transmission regions. There has been a decline …
Targeted amplicon deep sequencing for monitoring antimalarial resistance markers in Western Kenya
Molecular surveillance of Plasmodium falciparum parasites is important to track emerging
and new mutations and trends in established mutations and should serve as an early warning …
and new mutations and trends in established mutations and should serve as an early warning …
No Evidence of Plasmodium falciparum k13 Artemisinin Resistance-Conferring Mutations over a 24-Year Analysis in Coastal Kenya but a Near Complete Reversion …
…, L Ndwiga, V Osoti, KM Kimenyi… - Antimicrobial Agents …, 2019 - Am Soc Microbiol
Antimalarial drug resistance is a substantial impediment to malaria control. The spread of
resistance has been described using genetic markers, which are important epidemiological …
resistance has been described using genetic markers, which are important epidemiological …
Genetic connectivity of trypanosomes between tsetse-infested and tsetse-free areas of Kenya
The prevalence rates of trypanosomes, including those that require cyclical transmission by
tsetse flies, are widely distributed in Africa. Trypanosoma brucei and Trypanosoma …
tsetse flies, are widely distributed in Africa. Trypanosoma brucei and Trypanosoma …
No evidence of P. falciparum K13 artemisinin conferring mutations over a 24-year analysis in Coastal Kenya, but a near complete reversion to chloroquine wild type …
K Wamae, D Okanda, L Ndwiga, V Osoti, KM Kimenyi… - 2019 - erepository.uonbi.ac.ke
Antimalarial drug resistance is a substantial impediment to malaria control. The spread of
resistance has been described using genetic markers which are important epidemiological …
resistance has been described using genetic markers which are important epidemiological …
[HTML][HTML] Distinct transcriptomic signatures define febrile malaria depending on initial infective states, asymptomatic or uninfected
Background Cumulative malaria parasite exposure in endemic regions often results in the
acquisition of partial immunity and asymptomatic infections. There is limited information on …
acquisition of partial immunity and asymptomatic infections. There is limited information on …
[HTML][HTML] Comparative genomics identifies male accessory gland proteins in five Glossina species
MF Abry, KM Kimenyi, D Masiga… - Wellcome Open …, 2017 - ncbi.nlm.nih.gov
Accessory gland proteins (ACPs) are important reproductive proteins produced by the male
accessory glands (MAGs) of most insect species. These proteins are essential for male …
accessory glands (MAGs) of most insect species. These proteins are essential for male …