User profiles for Kelvin M. Kimenyi

Kelvin Muteru Kimenyi

University of Nairobi; KEMRI Wellcome Trust Research Programme
Verified email at kemri-wellcome.org
Cited by 200

[HTML][HTML] A review of the frequencies of Plasmodium falciparum Kelch 13 artemisinin resistance mutations in Africa

…, KM Kimenyi, K Wamae, V Osoti, M Akinyi… - International Journal for …, 2021 - Elsevier
Artemisinin resistance (AR) emerged in South East Asia 13 years ago and the identification
of the resistance conferring molecular marker, Plasmodium falciparum Kelch 13 (Pfk13), 7 …

[HTML][HTML] Understanding P. falciparum asymptomatic infections: a proposition for a transcriptomic approach

KM Kimenyi, K Wamae, LI Ochola-Oyier - Frontiers in Immunology, 2019 - frontiersin.org
Malaria is still a significant public health burden in the tropics. Infection with malaria causing
parasites results in a wide range of clinical disease presentations, from severe to …

Amplicon Sequencing as a Potential Surveillance Tool for Complexity of Infection and Drug Resistance Markers in Plasmodium falciparum Asymptomatic Infections

K Wamae, KM Kimenyi, V Osoti… - The Journal of …, 2022 - academic.oup.com
Background Genotyping Plasmodium falciparum subpopulations in malaria infections is an
important aspect of malaria molecular epidemiology to understand within-host diversity and …

[HTML][HTML] Maintenance of high temporal Plasmodium falciparum genetic diversity and complexity of infection in asymptomatic and symptomatic infections in Kilifi …

KM Kimenyi, K Wamae, JM Ngoi, ZR de Laurent… - Malaria Journal, 2022 - Springer
Background High levels of genetic diversity are common characteristics of Plasmodium
falciparum parasite populations in high malaria transmission regions. There has been a decline …

Targeted amplicon deep sequencing for monitoring antimalarial resistance markers in Western Kenya

V Osoti, M Akinyi, K Wamae, KM Kimenyi… - Antimicrobial Agents …, 2022 - Am Soc Microbiol
Molecular surveillance of Plasmodium falciparum parasites is important to track emerging
and new mutations and trends in established mutations and should serve as an early warning …

No Evidence of Plasmodium falciparum k13 Artemisinin Resistance-Conferring Mutations over a 24-Year Analysis in Coastal Kenya but a Near Complete Reversion …

…, L Ndwiga, V Osoti, KM Kimenyi… - Antimicrobial Agents …, 2019 - Am Soc Microbiol
Antimalarial drug resistance is a substantial impediment to malaria control. The spread of
resistance has been described using genetic markers, which are important epidemiological …

Genetic connectivity of trypanosomes between tsetse-infested and tsetse-free areas of Kenya

NN Kimenyi, KM Kimenyi, NO Amugune, MN Getahun - Parasitology, 2022 - cambridge.org
The prevalence rates of trypanosomes, including those that require cyclical transmission by
tsetse flies, are widely distributed in Africa. Trypanosoma brucei and Trypanosoma …

No evidence of P. falciparum K13 artemisinin conferring mutations over a 24-year analysis in Coastal Kenya, but a near complete reversion to chloroquine wild type …

K Wamae, D Okanda, L Ndwiga, V Osoti, KM Kimenyi… - 2019 - erepository.uonbi.ac.ke
Antimalarial drug resistance is a substantial impediment to malaria control. The spread of
resistance has been described using genetic markers which are important epidemiological …

[HTML][HTML] Distinct transcriptomic signatures define febrile malaria depending on initial infective states, asymptomatic or uninfected

KM Kimenyi, MY Akinyi, K Mwikali, T Gilmore… - BMC Infectious …, 2024 - Springer
Background Cumulative malaria parasite exposure in endemic regions often results in the
acquisition of partial immunity and asymptomatic infections. There is limited information on …

[HTML][HTML] Comparative genomics identifies male accessory gland proteins in five Glossina species

MF Abry, KM Kimenyi, D Masiga… - Wellcome Open …, 2017 - ncbi.nlm.nih.gov
Accessory gland proteins (ACPs) are important reproductive proteins produced by the male
accessory glands (MAGs) of most insect species. These proteins are essential for male …