Motivation: Transcriptome sequencing has long been the favored method for quickly and
inexpensively obtaining a large number of gene sequences from an organism with no …

The advent of next generation sequencing (NGS) has enabled investigations of the gut
microbiome with unprecedented resolution and throughput. This has stimulated the development …

Importance Fecal microbiota transplantation (FMT) is effective in preventing recurrentClostridium
difficileinfection (RCDI). However, it is not known whether clinical efficacy differs by …

Next-generation sequencing plays a central role in the characterization and quantification of
transcriptomes. Although numerous metrics are purported to quantify the quality of RNA, …

Inflammatory bowel diseases (IBD), Crohn's disease and ulcerative colitis, are poorly
understood disorders affecting the intestinal tract. The current model for disease suggests that …

Mycosis fungoides (MF) is a slowly progressive cutaneous T-cell lymphoma (CTCL) for
which there is no cure. In the early plaque stage, the disease is indolent, but development of …

Background RNA-Seq data is inherently nonuniform for different transcripts because of
differences in gene expression. This makes it challenging to decide how much data should be …

Full article: Effective fecal microbiota transplantation for recurrent Clostridioides difficile
infection in humans is associated with increased signalling in the bile acid-farnesoid X receptor-…

Mycosis fungoides (MF) is a mature T-cell lymphoma currently thought to develop primarily
in the skin by a clonal expansion of a transformed, resident memory T cell. However, this …

Domestic dogs have assisted humans for millennia. However, the extent to which these
helpful behaviors are prosocially motivated remains unclear. To assess the propensity of pet …