User profiles for Jihane Basbous
 | Jihane Basbous MesnardChargée de recherche, CNRS Verified email at igh.cnrs.fr Cited by 2265 |
The complementary strand of the human T-cell leukemia virus type 1 RNA genome encodes a bZIP transcription factor that down-regulates viral transcription
G Gaudray, F Gachon, J Basbous… - Journal of …, 2002 - Am Soc Microbiol
The RNA genome of the human T-cell leukemia virus type 1 (HTLV-1) codes for proteins
involved in infectivity, replication, and transformation. We report in this study the …
involved in infectivity, replication, and transformation. We report in this study the …
[HTML][HTML] The HBZ factor of human T-cell leukemia virus type I dimerizes with transcription factors JunB and c-Jun and modulates their transcriptional activity
J Basbous, C Arpin, G Gaudray, M Piechaczyk… - Journal of Biological …, 2003 - ASBMB
The human T-cell leukemia virus type I (HTLV-I)-encoded Tax protein activates transcription
from the viral promoter via association with the cellular basic leucine zipper factor cAMP-…
from the viral promoter via association with the cellular basic leucine zipper factor cAMP-…
[HTML][HTML] Premature activation of the SLX4 complex by Vpr promotes G2/M arrest and escape from innate immune sensing
N Laguette, C Brégnard, P Hue, J Basbous, A Yatim… - Cell, 2014 - cell.com
The HIV auxiliary protein Vpr potently blocks the cell cycle at the G2/M transition. Here, we
show that G2/M arrest results from untimely activation of the structure-specific endonuclease (…
show that G2/M arrest results from untimely activation of the structure-specific endonuclease (…
HBZ interacts with JunD and stimulates its transcriptional activity
S Thébault, J Basbous, P Hivin, C Devaux… - FEBS …, 2004 - Wiley Online Library
Human T‐cell leukemia virus type I (HTLV‐I) bZIP factor (HBZ) is a viral basic leucine zipper
protein that was originally described as a partner of cAMP response element binding protein…
protein that was originally described as a partner of cAMP response element binding protein…
Ubiquitin-independent proteasomal degradation of Fra-1 is antagonized by Erk1/2 pathway-mediated phosphorylation of a unique C-terminal destabilizer
J Basbous, D Chalbos, R Hipskind… - … and cellular biology, 2007 - Taylor & Francis
Fra-1, a transcription factor that is phylogenetically and functionally related to the proto-oncoprotein
c-Fos, controls many essential cell functions. It is expressed in many cell types, albeit …
c-Fos, controls many essential cell functions. It is expressed in many cell types, albeit …
[PDF][PDF] TopBP1 assembles nuclear condensates to switch on ATR signaling
…, M Lamarque, MP Blanchard, S Urbach, J Basbous… - Molecular cell, 2021 - cell.com
ATR checkpoint signaling is crucial for cellular responses to DNA replication impediments.
Using an optogenetic platform, we show that TopBP1, the main activator of ATR, self-…
Using an optogenetic platform, we show that TopBP1, the main activator of ATR, self-…
Nuclear localization of HTLV-I bZIP factor (HBZ) is mediated by three distinct motifs
…, M Frédéric, C Arpin-André, J Basbous… - Journal of cell …, 2005 - journals.biologists.com
The genome of the human T-cell leukemia virus type I (HTLV-I) codes for a basic leucine
zipper protein, HBZ, capable of repressing JUN activity and viral transcription. Transient …
zipper protein, HBZ, capable of repressing JUN activity and viral transcription. Transient …
[HTML][HTML] RECQ1 helicase is involved in replication stress survival and drug resistance in multiple myeloma
Multiple myeloma (MM) is a plasma cell cancer with poor survival, characterized by the
expansion of multiple myeloma cells (MMCs) in the bone marrow. Using a microarray-based …
expansion of multiple myeloma cells (MMCs) in the bone marrow. Using a microarray-based …
[HTML][HTML] The HBZ-SP1 isoform of human T-cell leukemia virus type I represses JunB activity by sequestration into nuclear bodies
P Hivin, J Basbous, F Raymond, D Henaff… - Retrovirology, 2007 - Springer
Background The human T-cell leukemia virus type I (HTLV-I) basic leucine-zipper factor (HBZ)
has previously been shown to modulate transcriptional activity of Jun family members. …
has previously been shown to modulate transcriptional activity of Jun family members. …
Ubiquitin-independent-versus ubiquitin-dependent proteasomal degradation of the c-Fos and Fra-1 transcription factors: is there a unique answer?
J Basbous, I Jariel-Encontre, T Gomard, G Bossis… - Biochimie, 2008 - Elsevier
The Fos family of transcription factors comprises c-Fos, Fra-1, Fra-2 and FosB, which are all
intrinsically unstable proteins. Fos proteins heterodimerize with a variety of other …
intrinsically unstable proteins. Fos proteins heterodimerize with a variety of other …