User profiles for Jason Cooper
 | Jason K Cooper (0000-0002-7953-4229)Twelve Benefit Corp Verified email at lbl.gov Cited by 5100 |
Common genetic determinants of vitamin D insufficiency: a genome-wide association study
…, C Ohlsson, DL Koller, L Peltonen, JD Cooper… - The Lancet, 2010 - thelancet.com
Background Vitamin D is crucial for maintenance of musculoskeletal health, and might also
have a role in extraskeletal tissues. Determinants of circulating 25-hydroxyvitamin D …
have a role in extraskeletal tissues. Determinants of circulating 25-hydroxyvitamin D …
Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes
JA Todd, NM Walker, JD Cooper, DJ Smyth… - Nature …, 2007 - nature.com
The Wellcome Trust Case Control Consortium (WTCCC) primary genome-wide association (GWA)
scan 1 on seven diseases, including the multifactorial autoimmune disease type 1 …
scan 1 on seven diseases, including the multifactorial autoimmune disease type 1 …
Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes
Type 1 diabetes (T1D) is a common autoimmune disorder that arises from the action of
multiple genetic and environmental risk factors. We report the findings of a genome-wide …
multiple genetic and environmental risk factors. We report the findings of a genome-wide …
[HTML][HTML] Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts
…, C Lu, E Tikkanen, S Pilz, LT Hiraki, JD Cooper… - PLoS …, 2013 - journals.plos.org
Background Obesity is associated with vitamin D deficiency, and both are areas of active
public health concern. We explored the causality and direction of the relationship between …
public health concern. We explored the causality and direction of the relationship between …
[HTML][HTML] Shared and distinct genetic variants in type 1 diabetes and celiac disease
…, V Plagnol, NM Walker, JD Cooper… - … England Journal of …, 2008 - Mass Medical Soc
Background Two inflammatory disorders, type 1 diabetes and celiac disease, cosegregate in
populations, suggesting a common genetic origin. Since both diseases are associated with …
populations, suggesting a common genetic origin. Since both diseases are associated with …
A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region
DJ Smyth, JD Cooper, R Bailey, S Field, O Burren… - Nature …, 2006 - nature.com
In this study we report convincing statistical support for a sixth type 1 diabetes (T1D) locus in
the innate immunity viral RNA receptor gene region IFIH1 (also known as mda-5 or Helicard…
the innate immunity viral RNA receptor gene region IFIH1 (also known as mda-5 or Helicard…
Tailored catalyst microenvironments for CO2 electroreduction to multicarbon products on copper using bilayer ionomer coatings
Electrochemical carbon dioxide reduction (CO 2 R) provides a promising pathway for
sustainable generation of fuels and chemicals. Copper (Cu) electrocatalysts catalyse CO 2 R to …
sustainable generation of fuels and chemicals. Copper (Cu) electrocatalysts catalyse CO 2 R to …
Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers
Genetic studies of type 1 diabetes (T1D) have identified 50 susceptibility regions 1 , 2 , finding
major pathways contributing to risk 3 , with some loci shared across immune disorders 4 , …
major pathways contributing to risk 3 , with some loci shared across immune disorders 4 , …
Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A
…, J Hulme, LM Maier, D Smyth, R Bailey, JD Cooper… - Nature, 2007 - nature.com
The major histocompatibility complex (MHC) on chromosome 6 is associated with susceptibility
to more common diseases than any other region of the human genome, including almost …
to more common diseases than any other region of the human genome, including almost …
Replication of an Association Between the Lymphoid Tyrosine Phosphatase Locus (LYP/PTPN22) With Type 1 Diabetes, and Evidence for Its Role as a General …
D Smyth, JD Cooper, JE Collins, JM Heward… - Diabetes, 2004 - Am Diabetes Assoc
In the genetic analysis of common, multifactorial diseases, such as type 1 diabetes, true positive
irrefutable linkage and association results have been rare to date. Recently, it has been …
irrefutable linkage and association results have been rare to date. Recently, it has been …