Dominantly inherited Alzheimer’s disease (DIAD) causes predictable biological changes
decades before the onset of clinical symptoms, enabling testing of interventions in the …

Background Rapid demographic ageing is a growing public health issue in many low- and
middle-income countries (LAMICs). Mild cognitive impairment (MCI) is a construct frequently …

Objectives: To identify novel loci for late-onset Alzheimer disease (LOAD) in Caribbean
Hispanic individuals and to replicate the findings in a publicly available data set from the …

Background Current estimates of the prevalence of depression in later life mostly arise from
studies carried out in Europe, North America and Asia. In this study we aimed to measure the …

Objective To detect rare coding variants underlying loci detected by genome‐wide association
studies (GWAS) of late onset Alzheimer disease (LOAD). Methods We conducted targeted …

Objectives To estimate the prevalence, social patterning, treatment and control of hypertension
among older people in the 10/66 Dementia Research Group developing country sites. …

Background The World Health Organization (WHO) has reframed health and healthcare for
older people around achieving the goal of healthy ageing. The recent WHO Integrated Care …

Background To describe patterns of recent health service utilisation, and consequent out-of-pocket
expenses among older people in countries with low and middle incomes, and to …

While two thirds of the 24 million people with dementia worldwide live in low and middle
income countries, very little research has been conducted to support policy making in these …

Population ageing is affecting low-and middle-income countries, with absolute and relative
numbers of older adults increasing quickly across the globe. This demographic transition is …