In order to elucidate the functional organization of the genome, it is vital to directly visualize
the interactions between genomic elements in living cells. For this purpose, we engineered …

We investigate the impact of say-on-pay on 2010 executive compensation, finding that
affected firms reduced compensation and made it more performance-based in advance of the …

We have developed a new open-top selective plane illumination microscope (SPIM)
compatible with microfluidic devices, multi-well plates, and other sample formats used in …

Background Larval zebrafish, with a simple and transparent vertebrate brain composed of ~100
K neurons, is well suited for deciphering entire neural circuit activity underlying behavior. …

Choline-based amino acid ionic liquids with anions glycinate, β-alaninate, phenylalaninate,
and prolinate were synthesized and mixed with ethylene glycol to form lower-viscosity …

Prior research shows that companies repurchase stock during quarters with low returns,
presumably because the stock is undervalued. We focus on repurchase increases and …

Parkinson’s disease (PD) is a common neurodegenerative disorder without effective
disease-modifying therapeutics. Here, we establish a chemogenetic dopamine (DA) neuron …

High-throughput screens at microscopic resolution can uncover molecular mechanisms of
cellular dynamics, but remain technically challenging in live multicellular organisms. Here we …

Nurr1, a nuclear receptor essential for the development, maintenance, and survival of
midbrain dopaminergic neurons, is a potential therapeutic target for Parkinson's disease, a …

Live imaging of genome has offered important insights into the dynamics of the genome
organization and gene expression. The demand to image simultaneously multiple genomic loci …