The human genome is extensively folded into 3-dimensional organization. However, the
detailed 3D chromatin folding structures have not been fully visualized due to the lack of robust …

Eukaryotic genomes are pervasively transcribed by RNA polymerase II. Yet, the molecular
and biological implications of such a phenomenon are still largely puzzling. Here, we …

Spatial chromatin organization is crucial for transcriptional regulation and might be particularly
important in neurons since they dramatically change their transcriptome in response to …

The detailed architectural examination of the neuronal nuclei in any brain region, using confocal
microscopy, requires quantification of fluorescent signals in three-dimensional stacks of …

The common approach in morphological analysis of dendritic spines of mammalian
neuronal cells is to categorize spines into subpopulations based on whether they are stubby, …

Production of morphologically and physiologically variable seeds is an important strategy
that helps plants to survive in unpredictable natural conditions. However, the model plant …

Background Bioimaging techniques offer a robust tool for studying molecular pathways and
morphological phenotypes of cell populations subjected to various conditions. As modern …

Neutrophil extracellular traps (NETs), pathogen-ensnaring structures formed by neutrophils
by expelling their DNA into the environment, are believed to play an important role in …

Genome-wide analysis of miRNA molecules can reveal important information for understanding
the biology of cancer. Typically, miRNAs are used as features in statistical learning …

In the Special Issue on Tools for Protein Science in 2018, we presented Molstack: a concept
of a cloud‐based platform for sharing electron density maps and their interpretations. …