Large-scale population genomic surveys are essential to explore the phenotypic diversity of
natural populations. Here we report the whole-genome sequencing and phenotyping of …

Progress in genome sequencing now enables the large-scale generation of reference genomes.
Various international initiatives aim to generate reference genomes representing global …

10.7554/eLife.05835.001 The budding yeast Saccharomyces cerevisiae has been used in
laboratory experiments for over a century and has been instrumental in understanding …

A fundamental goal in biology is to achieve a mechanistic understanding of how and to
what extent ecological variation imposes selection for distinct traits and favors the fixation of …

The availability of public genomic resources can greatly assist biodiversity assessment,
conservation, and restoration efforts by providing evidence for scientifically informed …

Evolve and resequence (E&R) experiments use experimental evolution to adapt populations
to a novel environment, then next-generation sequencing to analyse genetic changes. They …

Since the completion of the genome sequence of Saccharomyces cerevisiae in 1996 (refs 1
), there has been a large increase in complete genome sequences, accompanied by great …

… occurring hybrids between these species have been found (Liti … Liti et al. 2005) and that the
hybrid species S. pastorianus originated from several hybridizations rather than from one (Liti …

The budding yeast, S accharomyces cerevisiae, is a leading system in genetics, genomics
and molecular biology and is becoming a powerful tool to illuminate ecological and …

The question of how genetic variation in a population influences phenotypic variation and
evolution is of major importance in modern biology. Yet much is still unknown about the …