User profiles for Dina Zielinski
Dina ZielinskiFrench Institute of Health and Medical Research Verified email at inserm.fr Cited by 1768 |
DNA Fountain enables a robust and efficient storage architecture
Y Erlich, D Zielinski - science, 2017 - science.org
DNA is an attractive medium to store digital information. Here we report a storage strategy,
called DNA Fountain, that is highly robust and approaches the information capacity per …
called DNA Fountain, that is highly robust and approaches the information capacity per …
[HTML][HTML] COVID-19 pandemic and worldwide organ transplantation: a population-based study
Background Preliminary data suggest that COVID-19 has reduced access to solid organ
transplantation. However, the global consequences of the COVID-19 pandemic on …
transplantation. However, the global consequences of the COVID-19 pandemic on …
Genome-wide profiling of heritable and de novo STR variations
T Willems, D Zielinski, J Yuan, A Gordon, M Gymrek… - Nature …, 2017 - nature.com
Short tandem repeats (STRs) are highly variable elements that play a pivotal role in multiple
genetic diseases, population genetics applications, and forensic casework. However, it has …
genetic diseases, population genetics applications, and forensic casework. However, it has …
A cis-acting mechanism mediates transcriptional memory at Polycomb target genes in mammals
D Holoch, M Wassef, C Lövkvist, D Zielinski, S Aflaki… - Nature Genetics, 2021 - nature.com
Epigenetic inheritance of gene expression states enables a single genome to maintain distinct
cellular identities. How histone modifications contribute to this process remains unclear. …
cellular identities. How histone modifications contribute to this process remains unclear. …
[HTML][HTML] BAP1 complex promotes transcription by opposing PRC1-mediated H2A ubiquitylation
A Campagne, MK Lee, D Zielinski, A Michaud… - Nature …, 2019 - nature.com
In Drosophila, a complex consisting of Calypso and ASX catalyzes H2A deubiquitination
and has been reported to act as part of the Polycomb machinery in transcriptional silencing. …
and has been reported to act as part of the Polycomb machinery in transcriptional silencing. …
[HTML][HTML] EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells
…, IH Baymaz, S Diop, K Ancelin, D Zielinski… - Nature …, 2019 - nature.com
The Polycomb group of proteins is required for the proper orchestration of gene expression
due to its role in maintaining transcriptional silencing. It is composed of several chromatin …
due to its role in maintaining transcriptional silencing. It is composed of several chromatin …
[HTML][HTML] The Banff 2022 Kidney Meeting Report: reappraisal of microvascular inflammation and the role of biopsy-based transcript diagnostics
The XVI-th Banff Meeting for Allograft Pathology was held at Banff, Alberta, Canada, from 19th
to 23rd September 2022, as a joint meeting with the Canadian Society of Transplantation. …
to 23rd September 2022, as a joint meeting with the Canadian Society of Transplantation. …
EZH1/2 function mostly within canonical PRC2 and exhibit proliferation-dependent redundancy that shapes mutational signatures in cancer
…, A Luscan, S Aflaki, D Zielinski… - Proceedings of the …, 2019 - National Acad Sciences
Genetic mutations affecting chromatin modifiers are widespread in cancers. In malignant
peripheral nerve sheath tumors (MPNSTs), Polycomb repressive complex 2 (PRC2), which …
peripheral nerve sheath tumors (MPNSTs), Polycomb repressive complex 2 (PRC2), which …
[HTML][HTML] OTX2 duplication is implicated in hemifacial microsomia
D Zielinski, B Markus, M Sheikh, M Gymrek, C Chu… - PloS one, 2014 - journals.plos.org
Hemifacial microsomia (HFM) is the second most common facial anomaly after cleft lip and
palate. The phenotype is highly variable and most cases are sporadic. We investigated the …
palate. The phenotype is highly variable and most cases are sporadic. We investigated the …
Complicated legacies: The human genome at 20
Millions of people today have access to their personal genomic information. Direct-to-consumer
services and integration with other “big data” increasingly commoditize what was rightly …
services and integration with other “big data” increasingly commoditize what was rightly …