Importance The sequelae of gestational diabetes (GD) by contemporary criteria that diagnose
approximately twice as many women as previously used criteria are unclear. Objective To …

Birth weight (BW) has been shown to be influenced by both fetal and maternal factors and in
observational studies is reproducibly associated with future risk of adult metabolic diseases …

OBJECTIVE Whether hyperglycemia in utero less than overt diabetes is associated with
altered childhood glucose metabolism is unknown. We examined associations of gestational …

Precision medicine is part of the logical evolution of contemporary evidence-based medicine
that seeks to reduce errors and optimize outcomes when making medical decisions and …

Background Amplification and activating mutations of the epidermal growth factor receptor (EGFR)
oncogene are molecular hallmarks of glioblastomas. We hypothesized that deletion of …

Importance Neonates born to overweight or obese women are larger and at higher risk of
birth complications. Many maternal obesity-related traits are observationally associated with …

OBJECTIVE This study examined associations of maternal glycemia during pregnancy with
childhood glucose outcomes in the Hyperglycemia and Adverse Pregnancy Outcome (HAPO…

Aims/hypothesis Maternal type 2 diabetes during pregnancy and gestational diabetes are
associated with childhood adiposity; however, associations of lower maternal glucose levels …

Context Gliomas, particularly glioblastomas, are among the deadliest of human tumors.
Gliomas emerge through the accumulation of recurrent chromosomal alterations, some of which …

Genome-wide association studies of birth weight have focused on fetal genetics, whereas
relatively little is known about the role of maternal genetic variation. We aimed to identify …