Host-mediated lung inflammation is present 1 , and drives mortality 2 , in the critical illness
caused by coronavirus disease 2019 (COVID-19). Host genetic variants associated with …

Here we conducted a large-scale genetic association analysis of educational attainment in
a sample of approximately 1.1 million individuals and identify 1,271 independent genome-…

Major depression is a debilitating psychiatric illness that is typically associated with low
mood and anhedonia. Depression has a heritable component that has remained difficult to …

A balanced (1;11)(q42.1;q14.3) translocation segregates with schizophrenia and related
psychiatric disorders in a large Scottish family (maximum LOD = 6.0). We hypothesize that the …

We conduct a genome-wide association study (GWAS) of educational attainment (EA) in a
sample of~ 3 million individuals and identify 3,952 approximately uncorrelated genome-wide-…

Schizophrenia is a debilitating psychiatric condition often associated with poor quality of life
and decreased life expectancy. Lack of progress in improving treatment outcomes has been …

Educational attainment is strongly influenced by social and other environmental factors, but
genetic factors are estimated to account for at least 20% of the variation across individuals 1. …

Estimates from genome-wide association studies (GWAS) of unrelated individuals capture
effects of inherited variation (direct effects), demography (population stratification, assortative …

The frequency of, and risk factors for, long COVID are unclear among community-based
individuals with a history of COVID-19. To elucidate the burden and possible causes of long …

We report the results of a double-blind, placebo-controlled trial in nine cystic fibrosis (CF)
subjects receiving cationic liposome complexed with a complementary DNA encoding the CF …