Magnetoencephalography measures neuromagnetic activity with high temporal, and
theoretically, high spatial resolution. We developed an experimental platform combining MEG-…

Network excitability is governed by synaptic efficacy, intrinsic excitability, and the circuitry in
which these factors are expressed. The complex interplay between these factors determines …

Background Alcohol withdrawal syndrome (AWS) results from the sudden cessation of
chronic alcohol use and is associated with high morbidity and mortality. Alcohol withdrawal‐…

Background Performing optogenetic experiments in a behaving animal presents a unique
technical challenge. In order to provide an optical path between a fixed light source and a …

Previous studies have demonstrated a deficiency in mitochondrial function in Parkinson's
disease. We measured the ability of mitochondrial inhibitors of complexes I (rotenone, MPP + , …

Optogenetic proteins are powerful tools for advancing our understanding of neural circuitry.
However, the precision of optogenetics is dependent in part on the extent to which …

Tuberous sclerosis complex (TS) is a dominant, multisystem disorder with devastating
neurological symptoms. Approximately 85% of TS patients suffer from epilepsy over their lifespan …

Magnetoencephalography (MEG) measures neuromagnetic activity with high temporal, and
theoretically, high spatial resolution. However, the ability of magnetic source imaging (MSI) …

Here we report a novel method for assessing the intrinsic excitability of a local population
through in vitro optogenetic stimulation of hippocampal CA1, specifically deep excitatory cells …

Alcohol abuse is a large scale societal problem. Cessation of chronic alcohol use may produce
alcohol withdrawal syndrome (AWS), which is accompanied by significant public health …