User profiles for Claire E. Turner
 | Claire E TurnerUniversity of Sheffield Verified email at sheffield.ac.uk Cited by 1968 |
[PDF][PDF] The IL-8 protease SpyCEP/ScpC of group A Streptococcus promotes resistance to neutrophil killing
…, CE Turner, I Mishalian, S Sriskandan, E Hanski… - Cell host & …, 2008 - cell.com
Interleukin-8 (IL-8) promotes neutrophil-mediated host defense through its chemoattractant
and immunostimulatory activities. The Group A Streptococcus (GAS) protease SpyCEP (also …
and immunostimulatory activities. The Group A Streptococcus (GAS) protease SpyCEP (also …
[HTML][HTML] Emergence of dominant toxigenic M1T1 Streptococcus pyogenes clone during increased scarlet fever activity in England: a population-based molecular …
…, E Jauneikaite, HK Li, X Zhi, CE Turner… - The Lancet Infectious …, 2019 - thelancet.com
Background Since 2014, England has seen increased scarlet fever activity unprecedented in
modern times. In 2016, England's scarlet fever seasonal rise coincided with an unexpected …
modern times. In 2016, England's scarlet fever seasonal rise coincided with an unexpected …
Emergence of a New Highly Successful Acapsular Group A Streptococcus Clade of Genotype emm89 in the United Kingdom
Group A Streptococcus (GAS) genotype emm89 is increasingly recognized as a leading cause
of disease worldwide, yet factors that underlie the success of this emm type are unknown. …
of disease worldwide, yet factors that underlie the success of this emm type are unknown. …
[HTML][HTML] Human CEACAM1 is targeted by a Streptococcus pyogenes adhesin implicated in puerperal sepsis pathogenesis
…, M Lyndin, CE Turner… - Nature …, 2023 - nature.com
Life-threatening bacterial infections in women after childbirth, known as puerperal sepsis,
resulted in classical epidemics and remain a global health problem. While outbreaks of …
resulted in classical epidemics and remain a global health problem. While outbreaks of …
Chemokine‐cleaving Streptococcus pyogenes protease SpyCEP is necessary and sufficient for bacterial dissemination within soft tissues and the respiratory tract
P Kurupati, CE Turner, I Tziona… - Molecular …, 2010 - Wiley Online Library
SpyCEP is a Streptococcus pyogenes protease that cleaves CXCL8/IL‐8 and its activity is
associated with human invasive disease severity. We investigated the role of SpyCEP in S. …
associated with human invasive disease severity. We investigated the role of SpyCEP in S. …
Emerging Role of the Interleukin-8 Cleaving Enzyme SpyCEP in Clinical Streptococcus pyogenes Infection
CE Turner, P Kurupati, MD Jones… - The Journal of …, 2009 - academic.oup.com
Neutrophil chemoattractant interleukin (IL)–8 is cleaved and inactivated by the Streptococcus
pyogenes cell envelope protease SpyCEP. A range of clinical S. pyogenes strains of …
pyogenes cell envelope protease SpyCEP. A range of clinical S. pyogenes strains of …
[HTML][HTML] Inactivation of the CovR/S Virulence Regulator Impairs Infection in an Improved Murine Model of Streptococcus pyogenes Naso-Pharyngeal Infection
<p><italic>Streptococcus pyogenes</italic> is a leading cause of pharyngeal infection, with
an estimated 616 million cases per year. The human nasopharynx represents the major …
an estimated 616 million cases per year. The human nasopharynx represents the major …
[HTML][HTML] Clinical and molecular epidemiology of staphylococcal toxic shock syndrome in the United Kingdom
H Sharma, D Smith, CE Turner, L Game… - Emerging Infectious …, 2018 - ncbi.nlm.nih.gov
Staphylococcal toxic shock syndrome (TSS) was originally described in menstruating women
and linked to TSS toxin 1 (TSST-1)–producing Staphylococcus aureus. Using UK national …
and linked to TSS toxin 1 (TSST-1)–producing Staphylococcus aureus. Using UK national …
[HTML][HTML] RocA truncation underpins hyper-encapsulation, carriage longevity and transmissibility of serotype M18 group A streptococci
NN Lynskey, D Goulding, M Gierula, CE Turner… - PLoS …, 2013 - journals.plos.org
Group A streptococcal isolates of serotype M18 are historically associated with epidemic waves
of pharyngitis and the non-suppurative immune sequela rheumatic fever. The serotype is …
of pharyngitis and the non-suppurative immune sequela rheumatic fever. The serotype is …
[HTML][HTML] Extracellular bacterial lymphatic metastasis drives Streptococcus pyogenes systemic infection
Unassisted metastasis through the lymphatic system is a mechanism of dissemination thus
far ascribed only to cancer cells. Here, we report that Streptococcus pyogenes also hijack …
far ascribed only to cancer cells. Here, we report that Streptococcus pyogenes also hijack …