Quantitative analysis of plant and animal morphogenesis requires accurate segmentation of
individual cells in volumetric images of growing organs. In the last years, deep learning has …

Building expression constructs for transgenesis is one of the fundamental day-to-day tasks
in modern biology. Traditionally it is based on a multitude of type II restriction endonucleases …

To maintain the balance between long-term stem cell self-renewal and differentiation,
dynamic signals need to be translated into spatially precise and temporally stable gene …

The physical interaction of the plasma membrane with the associated cortical cytoskeleton
is important in many morphogenetic processes during development. At the end of the …

10.7554/eLife.30135.001 Plant meristems carry pools of continuously active stem cells, whose
activity is controlled by developmental and environmental signals. After stem cell division, …

Positional information is essential for coordinating the development of multicellular organisms.
In plants, positional information provided by the hormone auxin regulates rhythmic organ …

Background The shape of a nucleus depends on the nuclear lamina, which is tightly associated
with the inner nuclear membrane and on the interaction with the cytoskeleton. However, …

Spatial specificity of cell fate decisions is central for organismal development. The phloem
tissue mediates long-distance transport of energy metabolites along plant bodies and is …

Understanding the context-specific role of gene function is a key objective of modern biology.
To this end, we generated a resource for inducible cell type-specific transactivation in …

A key question in plant biology is how oriented cell divisions are integrated with patterning
mechanisms to generate organs with adequate cell type allocation. In the root vasculature, a …