CRISPR–Cas9 genome editing in human cells occurs via the Fanconi anemia pathway
CD Richardson, KR Kazane, SJ Feng, E Zelin… - Nature …, 2018 - nature.com
CRISPR–Cas genome editing creates targeted DNA double-strand breaks (DSBs) that are
processed by cellular repair pathways, including the incorporation of exogenous DNA via …
processed by cellular repair pathways, including the incorporation of exogenous DNA via …
[HTML][HTML] Timed inhibition of CDC7 increases CRISPR-Cas9 mediated templated repair
Repair of double strand DNA breaks (DSBs) can result in gene disruption or gene modification
via homology directed repair (HDR) from donor DNA. Altering cellular responses to DSBs …
via homology directed repair (HDR) from donor DNA. Altering cellular responses to DSBs …
[HTML][HTML] RIG-I is required for the inhibition of measles virus by retinoids
KJ Soye, C Trottier, CD Richardson, BJ Ward… - PloS one, 2011 - journals.plos.org
Vitamin A can significantly decrease measles-associated morbidity and mortality. Vitamin A
can inhibit the replication of measles virus (MeV) in vitro through an RARα- and type I …
can inhibit the replication of measles virus (MeV) in vitro through an RARα- and type I …
Nonlinear Schrödinger wave equation with linear quantum behavior
We show that a nonlinear Schrödinger wave equation can reproduce all the features of linear
quantum mechanics. This nonlinear wave equation is obtained by exploring, in a uniform …
quantum mechanics. This nonlinear wave equation is obtained by exploring, in a uniform …
[HTML][HTML] Interstrand crosslinking of homologous repair template DNA enhances gene editing in human cells
…, C Cruz, JT Vu, BM Gardner, CD Richardson - Nature …, 2023 - nature.com
We describe a strategy to boost the efficiency of gene editing via homology-directed repair (HDR)
by covalently modifying the template DNA with interstrand crosslinks. Crosslinked …
by covalently modifying the template DNA with interstrand crosslinks. Crosslinked …
CRISPR-Cas9 genome editing in human cells works via the Fanconi anemia pathway
CRISPR-Cas9 genome editing creates targeted double strand breaks (DSBs) in eukaryotic
cells that are processed by cellular DNA repair pathways. Co-administration of single …
cells that are processed by cellular DNA repair pathways. Co-administration of single …
[HTML][HTML] The N1 domain of the peroxisomal AAA-ATPase Pex6 is required for Pex15 binding and proper assembly with Pex1
…, DT Castanzo, KL Carr, CD Richardson… - Journal of Biological …, 2024 - ASBMB
The heterohexameric ATPases associated with diverse cellular activities (AAA)-ATPase
Pex1/Pex6 is essential for the formation and maintenance of peroxisomes. Pex1/Pex6, similar to …
Pex1/Pex6 is essential for the formation and maintenance of peroxisomes. Pex1/Pex6, similar to …
[HTML][HTML] Engineering water exchange is a safe and effective method for magnetic resonance imaging in diverse cell types
…, WD Miller, MA Morrissey, CD Richardson… - Journal of Biological …, 2024 - Springer
Aquaporin-1 (Aqp1), a water channel, has garnered significant interest for cell-based
medicine and in vivo synthetic biology due to its ability to be genetically encoded to produce …
medicine and in vivo synthetic biology due to its ability to be genetically encoded to produce …
Thwarting the photon-number-splitting attack with entanglement-enhanced BB84 quantum key distribution
CF Sabottke, CD Richardson, PM Anisimov… - New Journal of …, 2012 - iopscience.iop.org
We develop an improvement to the weak laser pulse BB84 scheme for quantum key
distribution, which utilizes entanglement to improve the security of the scheme and enhance its …
distribution, which utilizes entanglement to improve the security of the scheme and enhance its …
Positive identification of a measles virus cDNA clone encoding a region of the phosphoprotein
WJ Bellini, G Englund, CD Richardson… - Journal of …, 1984 - Am Soc Microbiol
A measles virus-specific cDNA clone, C1-G, that was previously assigned as a
hemagglutinin-specific clone has been reassigned as a phosphoprotein-specific clone. The …
hemagglutinin-specific clone has been reassigned as a phosphoprotein-specific clone. The …