User profiles for Chris C. Holmes

Chris Holmes

Verified email at stats.ox.ac.uk
Cited by 22026

Markov chain Monte Carlo methods and the label switching problem in Bayesian mixture modeling

A Jasra, CC Holmes, DA Stephens - 2005 - projecteuclid.org
In the past ten years there has been a dramatic increase of interest in the Bayesian analysis
of finite mixture models. This is primarily because of the emergence of Markov chain Monte …

Bayesian auxiliary variable models for binary and multinomial regression

L Held, CC Holmes - 2006 - projecteuclid.org
In this paper we discuss auxiliary variable approaches to Bayesian binary and multinomial
regression. These approaches are ideally suited to automated Markov chain Monte Carlo …

[HTML][HTML] Key issues in conducting a meta-analysis of gene expression microarray datasets

A Ramasamy, A Mondry, CC Holmes… - PLoS medicine, 2008 - journals.plos.org
… Michiels S, Koscielny S, Hill C (2005) Prediction of cancer outcome with microarrays: A
multiple random validation strategy. Lancet 365: 488–492. … Lapointe J, Li C, Higgins JP …

A general framework for updating belief distributions

PG Bissiri, CC Holmes, SG Walker - Journal of the Royal …, 2016 - academic.oup.com
We propose a framework for general Bayesian inference. We argue that a valid update of a
prior belief distribution to a posterior can be made for parameters which are connected to …

Analyzing nonstationary spatial data using piecewise Gaussian processes

HM Kim, BK Mallick, CC Holmes - Journal of the American …, 2005 - Taylor & Francis
In many problems in geostatistics the response variable of interest is strongly related to the
underlying geology of the spatial location. In these situations there is often little correlation in …

Distinct developmental profile of lower-body adipose tissue defines resistance against obesity-associated metabolic complications

…, MolPAGE Consortium, MI McCarthy, CC Holmes… - Diabetes, 2014 - Am Diabetes Assoc
Upper- and lower-body fat depots exhibit opposing associations with obesity-related metabolic
disease. We defined the relationship between DEXA-quantified fat depots and diabetes/…

Human metabolic profiles are stably controlled by genetic and environmental variation

…, E Holmes, D Baunsgaard, CC Holmes - Molecular systems …, 2011 - embopress.org
1 H Nuclear Magnetic Resonance spectroscopy ( 1 H NMR) is increasingly used to measure
metabolite concentrations in sets of biological samples for top‐down systems biology and …

[HTML][HTML] Methods for qPCR gene expression profiling applied to 1440 lymphoblastoid single cells

…, K Datta, R Mittal, AJ Goldson, DW Sexton, CC Holmes - Methods, 2013 - Elsevier
The stochastic nature of generating eukaryotic transcripts challenges conventional methods
for obtaining and analyzing single-cell gene expression data. In order to address the …

Statistical inference with exchangeability and martingales

CC Holmes, SG Walker - Philosophical Transactions of …, 2023 - royalsocietypublishing.org
In this paper, we start by reviewing exchangeability and its relevance to the Bayesian approach.
We highlight the predictive nature of Bayesian models and the symmetry assumptions …

Assigning a value to a power likelihood in a general Bayesian model

CC Holmes, SG Walker - Biometrika, 2017 - academic.oup.com
… CC Holmes , CC HolmesHolmes gratefully acknowledges support from the Oxford-Man
Institute, the Alan Turing Institute, the Medical Research Council, UK, and the UK …