[HTML][HTML] Plasmids and Rickettsial Evolution: Insight from Rickettsia felis
…, NC Ammerman, JM Shallom, A Purkayastha… - PloS one, 2007 - journals.plos.org
Background The genome sequence of Rickettsia felis revealed a number of rickettsial genetic
anomalies that likely contribute not only to a large genome size relative to other rickettsiae, …
anomalies that likely contribute not only to a large genome size relative to other rickettsiae, …
[HTML][HTML] Rickettsia Phylogenomics: Unwinding the Intricacies of Obligate Intracellular Life
…, ND Vishnubhat, R Wattam, A Purkayastha… - PloS one, 2008 - journals.plos.org
Background Completed genome sequences are rapidly increasing for Rickettsia, obligate
intracellular α-proteobacteria responsible for various human diseases, including epidemic …
intracellular α-proteobacteria responsible for various human diseases, including epidemic …
A Family of acr-Coregulated Mycobacterium tuberculosis Genes Shares a Common DNA Motif and Requires Rv3133c (dosR or devR) for Expression
MA Florczyk, LA McCue, A Purkayastha… - Infection and …, 2003 - Am Soc Microbiol
Previous work has shown that the divergently transcribed Mycobacterium tuberculosis genes
acr (hspX, Rv2031c) and acg (Rv2032) are induced under conditions of shallow standing …
acr (hspX, Rv2031c) and acg (Rv2032) are induced under conditions of shallow standing …
Identification of a Mycobacterium tuberculosis Putative Classical Nitroreductase Gene Whose Expression Is Coregulated with That of the acr Gene within …
A Purkayastha, LA McCue… - Infection and …, 2002 - Am Soc Microbiol
Tuberculosis remains a leading killer worldwide, and new approaches for its treatment and
prevention are urgently needed. This effort will benefit greatly from a better understanding of …
prevention are urgently needed. This effort will benefit greatly from a better understanding of …
Genomic and bioinformatics analysis of HAdV-4, a human adenovirus causing acute respiratory disease: implications for gene therapy and vaccine vector …
A Purkayastha, SE Ditty, J Su, J McGraw… - Journal of …, 2005 - Am Soc Microbiol
Human adenovirus serotype 4 (HAdV-4) is a reemerging viral pathogenic agent implicated
in epidemic outbreaks of acute respiratory disease (ARD). This report presents a genomic …
in epidemic outbreaks of acute respiratory disease (ARD). This report presents a genomic …
Identification of targetable molecular alterations in the NCI-COG Pediatric MATCH trial.
…, B Coffey, PM Williams, SR Hamilton, A Purkayastha… - 2019 - ascopubs.org
10011 Background: The screening protocol for the NCI-Children’s Oncology Group (COG)
Pediatric Molecular Analysis for Therapy Choice (MATCH) trial detects tumor alterations that …
Pediatric Molecular Analysis for Therapy Choice (MATCH) trial detects tumor alterations that …
[HTML][HTML] Enabling precision medicine via standard communication of HTS provenance, analysis, and results
…, A Bell, A Hayes, A Suresh, A Purkayastha… - PLoS …, 2018 - journals.plos.org
A personalized approach based on a patient's or pathogen’s unique genomic sequence is
the foundation of precision medicine. Genomic findings must be robust and reproducible, and …
the foundation of precision medicine. Genomic findings must be robust and reproducible, and …
[HTML][HTML] Co-infections of adenovirus species in previously vaccinated patients
…, M Irvine, D Seto, A Purkayastha… - Emerging infectious …, 2006 - ncbi.nlm.nih.gov
Despite the success of the adenovirus vaccine administered to US military trainees, acute
respiratory disease (ARD) surveillance still detected breakthrough infections (respiratory …
respiratory disease (ARD) surveillance still detected breakthrough infections (respiratory …
Fluorescence-based detection of lacZ reporter gene expression in intact and viable bacteria including Mycobacterium species
B Rowland, A Purkayastha, C Monserrat… - FEMS microbiology …, 1999 - academic.oup.com
A variety of fluorescein di-β-d-galactopyranoside (FDG)-based substrates were evaluated
for measuring β-galactosidase expression in bacteria. One substrate, 5-acetylamino-FDG (…
for measuring β-galactosidase expression in bacteria. One substrate, 5-acetylamino-FDG (…
Genomic and bioinformatics analyses of HAdV-4vac and HAdV-7vac, two human adenovirus (HAdV) strains that constituted original prophylaxis against HAdV-related …
A Purkayastha, J Su, J McGraw, SE Ditty… - Journal of clinical …, 2005 - Am Soc Microbiol
Vaccine strains of human adenovirus serotypes 4 and 7 (HAdV-4vac and HAdV-7vac) have
been used successfully to prevent adenovirus-related acute respiratory disease outbreaks. …
been used successfully to prevent adenovirus-related acute respiratory disease outbreaks. …