[HTML][HTML] Spinal muscular atrophy diagnosis and carrier screening from genome sequencing data
X Chen, A Sanchis-Juan, CE French, AJ Connell… - Genetics in …, 2020 - nature.com
Purpose Spinal muscular atrophy (SMA), caused by loss of the SMN1 gene, is a leading
cause of early childhood death. Due to the near identical sequences of SMN1 and SMN2, …
cause of early childhood death. Due to the near identical sequences of SMN1 and SMN2, …
[HTML][HTML] Sunbeam: an extensible pipeline for analyzing metagenomic sequencing experiments
Background Analysis of mixed microbial communities using metagenomic sequencing
experiments requires multiple preprocessing and analytical steps to interpret the microbial and …
experiments requires multiple preprocessing and analytical steps to interpret the microbial and …
Angle of arrival estimation using decawave DW1000 integrated circuits
I Dotlic, A Connell, H Ma, J Clancy… - 2017 14th Workshop …, 2017 - ieeexplore.ieee.org
The paper describes principles of angle of arrival estimation using an anchor and a tag
which are built around Decawave's DW1000 impulse radio ultra-wideband IC. Typical …
which are built around Decawave's DW1000 impulse radio ultra-wideband IC. Typical …
[HTML][HTML] Lifestyle and the presence of helminths is associated with gut microbiome composition in Cameroonians
MA Rubel, A Abbas, LJ Taylor, A Connell, C Tanes… - Genome biology, 2020 - Springer
Background African populations provide a unique opportunity to interrogate host-microbe co-evolution
and its impact on adaptive phenotypes due to their genomic, phenotypic, and …
and its impact on adaptive phenotypes due to their genomic, phenotypic, and …
A place-based system? Regional policy levers and the UK's productivity challenge
National governments are increasingly focusing on ‘place’ in attempts to tackle economic
challenges. This puts pressure on regions to deliver productivity improvements. Drawing from …
challenges. This puts pressure on regions to deliver productivity improvements. Drawing from …
Engineered coatings for titanium implants to present ultralow doses of BMP-7
…, V Moulisová, A Leal-Egaña, A Connell… - ACS biomaterials …, 2018 - ACS Publications
The ongoing research to improve the clinical outcome of titanium implants has resulted in the
implemetation of multiple approches to deliver osteogenic growth factors accelerating and …
implemetation of multiple approches to deliver osteogenic growth factors accelerating and …
[HTML][HTML] Evaluation of the orally bioavailable 4-phenylbutyrate-tethered trichostatin A analogue AR42 in models of spinal muscular atrophy
CJ Lumpkin, AW Harris, AJ Connell, RW Kirk… - Scientific Reports, 2023 - nature.com
Proximal spinal muscular atrophy (SMA) is a leading genetic cause for infant death in the
world and results from the selective loss of motor neurons in the spinal cord. SMA is a …
world and results from the selective loss of motor neurons in the spinal cord. SMA is a …
Ranging methods utilizing carrier frequency offset estimation
I Dotlic, A Connell, M McLaughlin - 2018 15th Workshop on …, 2018 - ieeexplore.ieee.org
Precise digital estimation of Carrier Frequency Offset (CFO) between transmitter and
receiver is an inherent part of the frame reception in some coherent radio architectures, eg, …
receiver is an inherent part of the frame reception in some coherent radio architectures, eg, …
[HTML][HTML] Ruxolitinib cream has dual efficacy on pruritus and inflammation in experimental dermatitis
MD Scuron, BL Fay, AJ Connell, MT Peel… - Frontiers in …, 2021 - frontiersin.org
The goal of this study was to elucidate the anti-pruritic and anti-inflammatory efficacy of
ruxolitinib cream in experimentally-induced dermatitis. Atopic dermatitis (AD), the most common …
ruxolitinib cream in experimentally-induced dermatitis. Atopic dermatitis (AD), the most common …
Making sense of knowledge-brokering organisations: boundary organisations or policy entrepreneurs?
E MacKillop, A Connell, J Downe… - Science and Public …, 2023 - academic.oup.com
Abstract Knowledge-brokering organisations (KBOs) have multiplied in the evidence–policy
landscape worldwide, changing how decision-makers are accessing evidence. Yet, we still …
landscape worldwide, changing how decision-makers are accessing evidence. Yet, we still …