User profiles for Amina Noor
 | Amina NoorUniversity of California, San Diego Verified email at ucsd.edu Cited by 3697 |
[HTML][HTML] The effects of common structural variants on 3D chromatin structure
O Shanta, A Noor, J Sebat - BMC genomics, 2020 - Springer
Background Three-dimensional spatial organization of chromosomes is defined by highly
self-interacting regions 0.1–1 Mb in size termed Topological Associating Domains (TADs). …
self-interacting regions 0.1–1 Mb in size termed Topological Associating Domains (TADs). …
Inferring gene regulatory networks via nonlinear state-space models and exploiting sparsity
This paper considers the problem of learning the structure of gene regulatory networks from
gene expression time series data. A more realistic scenario when the state space model …
gene expression time series data. A more realistic scenario when the state space model …
[HTML][HTML] An integrated map of structural variation in 2,504 human genomes
Structural variants are implicated in numerous diseases and make up the majority of varying
nucleotides among human genomes. Here we describe an integrated set of eight structural …
nucleotides among human genomes. Here we describe an integrated set of eight structural …
[HTML][HTML] Multi-platform discovery of haplotype-resolved structural variation in human genomes
The incomplete identification of structural variants (SVs) from whole-genome sequencing
data limits studies of human genetic diversity and disease association. Here, we apply a suite …
data limits studies of human genetic diversity and disease association. Here, we apply a suite …
[PDF][PDF] Frequency and complexity of de novo structural mutation in autism
Genetic studies of autism spectrum disorder (ASD) have established that de novo duplications
and deletions contribute to risk. However, ascertainment of structural variants (SVs) has …
and deletions contribute to risk. However, ascertainment of structural variants (SVs) has …
[HTML][HTML] Common DNA sequence variation influences 3-dimensional conformation of the human genome
Background The 3-dimensional (3D) conformation of chromatin inside the nucleus is integral
to a variety of nuclear processes including transcriptional regulation, DNA replication, and …
to a variety of nuclear processes including transcriptional regulation, DNA replication, and …
[HTML][HTML] An overview of the statistical methods used for inferring gene regulatory networks and protein-protein interaction networks
The large influx of data from high-throughput genomic and proteomic technologies has
encouraged the researchers to seek approaches for understanding the structure of gene …
encouraged the researchers to seek approaches for understanding the structure of gene …
ROBNCA: robust network component analysis for recovering transcription factor activities
Motivation: Network component analysis (NCA) is an efficient method of reconstructing the
transcription factor activity (TFA), which makes use of the gene expression data and prior …
transcription factor activity (TFA), which makes use of the gene expression data and prior …
Campylobacter jejuni Enteritis
…, L Lee, AL Bourgeois, NED Amina… - Clinical infectious …, 2001 - academic.oup.com
We report the development of Campylobacter jejuni enteritis in a patient with preexisting
humoral and cellular immune recognition of C. jejuni antigens. This is one of few studies in …
humoral and cellular immune recognition of C. jejuni antigens. This is one of few studies in …
A closed-form solution for transcription factor activity estimation using network component analysis
Non-iterative network component analysis (NINCA), proposed by Jacklin at.al, employs
convex optimization methods to estimate the transcription factor control strengths and …
convex optimization methods to estimate the transcription factor control strengths and …