[HTML][HTML] Histone demethylases and their roles in cancer epigenetics
A D'Oto, Q Tian, AM Davidoff, J Yang - Journal of medical oncology …, 2016 - ncbi.nlm.nih.gov
The genetic abnormalities that drive tumorigenesis are usually coupled with epigenetic
alterations, such as DNA methylation and aberrant histone modifications, which may help …
alterations, such as DNA methylation and aberrant histone modifications, which may help …
[HTML][HTML] KDM6B promotes activation of the oncogenic CDK4/6-pRB-E2F pathway by maintaining enhancer activity in MYCN-amplified neuroblastoma
The H3K27me2/me3 histone demethylase KDM6B is essential to neuroblastoma cell survival.
However, the mechanism of KDM6B action remains poorly defined. We demonstrate that …
However, the mechanism of KDM6B action remains poorly defined. We demonstrate that …
Association of genre of singing and phonotraumatic vocal fold lesions in singers
LF Childs, A D'Oto, DR Beams, L Hynan… - The …, 2023 - Wiley Online Library
Objectives/Hypothesis To determine if (1) the likelihood of presenting with phonotraumatic
lesions differs by singing genre in treatment‐seeking singers and (2) if the distribution of …
lesions differs by singing genre in treatment‐seeking singers and (2) if the distribution of …
Characteristics of Idiopathic Subglottic Stenosis in the Elderly
A D'Oto, H Baker, T Mau, LF Childs… - The …, 2023 - Wiley Online Library
Objective To compare characteristics of patients ≥65 years presenting with idiopathic
subglottic stenosis (iSGS) to patients diagnosed at <65 years. We hypothesize that the groups …
subglottic stenosis (iSGS) to patients diagnosed at <65 years. We hypothesize that the groups …
Voice Therapy Expectations for Injured Singers
LF Childs, A D'Oto, A Harris, A Rao, T Mau - Journal of Voice, 2022 - Elsevier
Objectives/Hypothesis Voice therapy is a mainstay treatment modality in the management of
phonotrauma in singers. However, the typical duration of therapy an injured singer …
phonotrauma in singers. However, the typical duration of therapy an injured singer …
[PDF][PDF] KDM6B promotes oncogenic CDK4/6-pRB-E2F pathway via maintaining enhancer activation in high-risk neuroblastoma
A D'oto, J Fang, H Jin, B Xu, S Singh, A Mullasseril… - BioRxiv., 2020 - scholar.archive.org
… pathway via maintaining enhancer activation in high-risk neuroblastoma Alexandra D’Oto …
While Rb1 loss is very rare in neuroblastoma, several studies have shown that the Cyclin D/…
While Rb1 loss is very rare in neuroblastoma, several studies have shown that the Cyclin D/…
Safety and efficacy of sphenopalatine artery ligation in recalcitrant pediatric epistaxis
DD Alexandra, S Cox, P Svider, S Rangarajan… - International Journal of …, 2019 - Elsevier
Background Epistaxis is a common cause for emergency department visits for both children
and adults. In particular, posterior bleeds can be difficult to identify and treat. In adults, …
and adults. In particular, posterior bleeds can be difficult to identify and treat. In adults, …
An Indolent Middle Ear Mass
A D'Oto, AM Tolisano, B Isaacson - JAMA Otolaryngology–Head …, 2019 - jamanetwork.com
Discussion Meningiomas are benign intracranial neoplasms that may occur wherever the
meninges are found and most commonly along the parasagittal regions and large dural …
meninges are found and most commonly along the parasagittal regions and large dural …
The Impact of Working from Home on Employees
A Doto, J Erdman, L Horn, M Shannon - 2023 - digitalcommons.sacredheart.edu
Many people are now working from home as a result of the COVID-19 pandemic and the
goal of this study is to analyze the effect that this has on how we flourish and the feelings of …
goal of this study is to analyze the effect that this has on how we flourish and the feelings of …
Counting Collections 3–5
JK Schwerdtfeger, DF Doto - Choral Counting & Counting …, 2023 - taylorfrancis.com
… Maya and Alex are moving all of the yellow “flats,” representing 100 each, out of a large
basket and stacking them into cubes of 1,000. Maya diligently recounts the total each time Alex …
basket and stacking them into cubes of 1,000. Maya diligently recounts the total each time Alex …