Abstract Changes in cell fate and identity are essential for endothelial-to-haematopoietic
transition (EHT), an embryonic process that generates the first adult populations of …

The transcriptional pathways activated downstream of vascular endothelial growth factor (VEGF)
signaling during angiogenesis remain incompletely characterized. By assessing the …

Human genetic studies identified a strong association between loss of function mutations in
RBFOX2 and hypoplastic left heart syndrome (HLHS). There are currently no Rbfox2 mouse …

Canonical Notch signaling requires the presence of a membrane bound ligand and a
corresponding transmembrane Notch receptor. Receptor engagement induces multiple proteolytic …

The zebrafish Danio rerio is a powerful model system to study the genetics of development
and disease. However, maintenance of zebrafish husbandry records is both time intensive …

Establishing a functional circulatory system is required for post-implantation development
during murine embryogenesis. Previous studies in loss-of-function mouse models showed that …

The establishment of a functional circulatory system is required for post-implantation
development during murine embryogenesis. Previous studies in loss of function mouse models …

… This is the challenge that Paula M. Rhyner and the contributing authors take on in a com…
Rhyner and the contributors assume this all-inclusive voice in stitching together potential …

Screening the language abilities of African American kindergarten children with low socioeconomic
status (SES) poses a major challenge for many speech-language pathologists. This …

Advances in genetic engineering and biotechnology, in parallel to increased understanding
of disease processes and mechanisms of protective immunity, have facilitated the …