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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2009 3
2010 8
2011 5
2012 5
2013 10
2014 5
2015 10
2016 10
2017 11
2018 7
2019 7
2020 2
2021 2
2022 4
2023 1
2024 0

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71 results

Results by year

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Page 1
A comprehensive map of molecular drug targets.
Santos R, Ursu O, Gaulton A, Bento AP, Donadi RS, Bologa CG, Karlsson A, Al-Lazikani B, Hersey A, Oprea TI, Overington JP. Santos R, et al. Among authors: ursu o. Nat Rev Drug Discov. 2017 Jan;16(1):19-34. doi: 10.1038/nrd.2016.230. Epub 2016 Dec 2. Nat Rev Drug Discov. 2017. PMID: 27910877 Free PMC article. Review.
Massively parallel phenotyping of coding variants in cancer with Perturb-seq.
Ursu O, Neal JT, Shea E, Thakore PI, Jerby-Arnon L, Nguyen L, Dionne D, Diaz C, Bauman J, Mosaad MM, Fagre C, Lo A, McSharry M, Giacomelli AO, Ly SH, Rozenblatt-Rosen O, Hahn WC, Aguirre AJ, Berger AH, Regev A, Boehm JS. Ursu O, et al. Nat Biotechnol. 2022 Jun;40(6):896-905. doi: 10.1038/s41587-021-01160-7. Epub 2022 Jan 20. Nat Biotechnol. 2022. PMID: 35058622
Unexplored therapeutic opportunities in the human genome.
Oprea TI, Bologa CG, Brunak S, Campbell A, Gan GN, Gaulton A, Gomez SM, Guha R, Hersey A, Holmes J, Jadhav A, Jensen LJ, Johnson GL, Karlson A, Leach AR, Ma'ayan A, Malovannaya A, Mani S, Mathias SL, McManus MT, Meehan TF, von Mering C, Muthas D, Nguyen DT, Overington JP, Papadatos G, Qin J, Reich C, Roth BL, Schürer SC, Simeonov A, Sklar LA, Southall N, Tomita S, Tudose I, Ursu O, Vidovic D, Waller A, Westergaard D, Yang JJ, Zahoránszky-Köhalmi G. Oprea TI, et al. Among authors: ursu o. Nat Rev Drug Discov. 2018 May;17(5):317-332. doi: 10.1038/nrd.2018.14. Epub 2018 Mar 23. Nat Rev Drug Discov. 2018. PMID: 29472638 Free PMC article. Review.
BDDCS, the Rule of 5 and drugability.
Benet LZ, Hosey CM, Ursu O, Oprea TI. Benet LZ, et al. Among authors: ursu o. Adv Drug Deliv Rev. 2016 Jun 1;101:89-98. doi: 10.1016/j.addr.2016.05.007. Epub 2016 May 13. Adv Drug Deliv Rev. 2016. PMID: 27182629 Free PMC article. Review.
DrugCentral 2018: an update.
Ursu O, Holmes J, Bologa CG, Yang JJ, Mathias SL, Stathias V, Nguyen DT, Schürer S, Oprea T. Ursu O, et al. Nucleic Acids Res. 2019 Jan 8;47(D1):D963-D970. doi: 10.1093/nar/gky963. Nucleic Acids Res. 2019. PMID: 30371892 Free PMC article.
DrugCentral: online drug compendium.
Ursu O, Holmes J, Knockel J, Bologa CG, Yang JJ, Mathias SL, Nelson SJ, Oprea TI. Ursu O, et al. Nucleic Acids Res. 2017 Jan 4;45(D1):D932-D939. doi: 10.1093/nar/gkw993. Epub 2016 Oct 26. Nucleic Acids Res. 2017. PMID: 27789690 Free PMC article.
Novel drug targets in 2018.
Ursu O, Glick M, Oprea T. Ursu O, et al. Nat Rev Drug Discov. 2019 Mar 26. doi: 10.1038/d41573-019-00052-5. Online ahead of print. Nat Rev Drug Discov. 2019. PMID: 31048796 No abstract available.
Protein biomarker druggability profiling.
Mani S, Cannon D, Ohls R, Oprea T, Mathias S, Ballard K, Ursu O, Bologa C. Mani S, et al. Among authors: ursu o. J Biomed Inform. 2017 Feb;66:241-247. doi: 10.1016/j.jbi.2017.01.014. Epub 2017 Jan 25. J Biomed Inform. 2017. PMID: 28131723 Free PMC article.
71 results