Sequenceserver: A Modern Graphical User Interface for Custom BLAST Databases

Mol Biol Evol. 2019 Dec 1;36(12):2922-2924. doi: 10.1093/molbev/msz185.

Abstract

Comparing newly obtained and previously known nucleotide and amino-acid sequences underpins modern biological research. BLAST is a well-established tool for such comparisons but is challenging to use on new data sets. We combined a user-centric design philosophy with sustainable software development approaches to create Sequenceserver, a tool for running BLAST and visually inspecting BLAST results for biological interpretation. Sequenceserver uses simple algorithms to prevent potential analysis errors and provides flexible text-based and visual outputs to support researcher productivity. Our software can be rapidly installed for use by individuals or on shared servers.

Keywords: BLAST; comparative genomics; sequence analysis; visualization.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Computational Biology / methods*
  • Genetic Techniques*
  • Software*