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In vivo screening characterizes chromatin factor functions during normal and malignant hematopoiesis.
Lara-Astiaso D, Goñi-Salaverri A, Mendieta-Esteban J, Narayan N, Del Valle C, Gross T, Giotopoulos G, Beinortas T, Navarro-Alonso M, Aguado-Alvaro LP, Zazpe J, Marchese F, Torrea N, Calvo IA, Lopez CK, Alignani D, Lopez A, Saez B, Taylor-King JP, Prosper F, Fortelny N, Huntly BJP. Lara-Astiaso D, et al. Among authors: taylor king jp. Nat Genet. 2023 Sep;55(9):1542-1554. doi: 10.1038/s41588-023-01471-2. Epub 2023 Aug 14. Nat Genet. 2023. PMID: 37580596 Free PMC article.
scPerturb: harmonized single-cell perturbation data.
Peidli S, Green TD, Shen C, Gross T, Min J, Garda S, Yuan B, Schumacher LJ, Taylor-King JP, Marks DS, Luna A, Blüthgen N, Sander C. Peidli S, et al. Among authors: taylor king jp. Nat Methods. 2024 Mar;21(3):531-540. doi: 10.1038/s41592-023-02144-y. Epub 2024 Jan 26. Nat Methods. 2024. PMID: 38279009
RECOVER identifies synergistic drug combinations in vitro through sequential model optimization.
Bertin P, Rector-Brooks J, Sharma D, Gaudelet T, Anighoro A, Gross T, Martínez-Peña F, Tang EL, Suraj MS, Regep C, Hayter JBR, Korablyov M, Valiante N, van der Sloot A, Tyers M, Roberts CES, Bronstein MM, Lairson LL, Taylor-King JP, Bengio Y. Bertin P, et al. Among authors: taylor king jp. Cell Rep Methods. 2023 Oct 23;3(10):100599. doi: 10.1016/j.crmeth.2023.100599. Epub 2023 Oct 4. Cell Rep Methods. 2023. PMID: 37797618 Free PMC article.
Utilizing graph machine learning within drug discovery and development.
Gaudelet T, Day B, Jamasb AR, Soman J, Regep C, Liu G, Hayter JBR, Vickers R, Roberts C, Tang J, Roblin D, Blundell TL, Bronstein MM, Taylor-King JP. Gaudelet T, et al. Among authors: taylor king jp. Brief Bioinform. 2021 Nov 5;22(6):bbab159. doi: 10.1093/bib/bbab159. Brief Bioinform. 2021. PMID: 34013350 Free PMC article.
14 results