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Page 1
Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader.
Elife. 2022 Feb 18;11:e74175. doi: 10.7554/eLife.74175.
Elife. 2022.
PMID: 35179493
Free PMC article.
A thermophilic phage uses a small terminase protein with a fixed helix-turn-helix geometry.
Hayes JA, Hilbert BJ, Gaubitz C, Stone NP, Kelch BA.
Hayes JA, et al. Among authors: stone np.
J Biol Chem. 2020 Mar 20;295(12):3783-3793. doi: 10.1074/jbc.RA119.012224. Epub 2020 Feb 3.
J Biol Chem. 2020.
PMID: 32014998
Free PMC article.
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Principles for enhancing virus capsid capacity and stability from a thermophilic virus capsid structure.
Stone NP, Demo G, Agnello E, Kelch BA.
Stone NP, et al.
Nat Commun. 2019 Oct 2;10(1):4471. doi: 10.1038/s41467-019-12341-z.
Nat Commun. 2019.
PMID: 31578335
Free PMC article.
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Structure of the human clamp loader reveals an autoinhibited conformation of a substrate-bound AAA+ switch.
Gaubitz C, Liu X, Magrino J, Stone NP, Landeck J, Hedglin M, Kelch BA.
Gaubitz C, et al. Among authors: stone np.
Proc Natl Acad Sci U S A. 2020 Sep 22;117(38):23571-23580. doi: 10.1073/pnas.2007437117. Epub 2020 Sep 9.
Proc Natl Acad Sci U S A. 2020.
PMID: 32907938
Free PMC article.
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Structure and mechanism of the ATPase that powers viral genome packaging.
Hilbert BJ, Hayes JA, Stone NP, Duffy CM, Sankaran B, Kelch BA.
Hilbert BJ, et al. Among authors: stone np.
Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):E3792-9. doi: 10.1073/pnas.1506951112. Epub 2015 Jul 6.
Proc Natl Acad Sci U S A. 2015.
PMID: 26150523
Free PMC article.
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A Hyperthermophilic Phage Decoration Protein Suggests Common Evolutionary Origin with Herpesvirus Triplex Proteins and an Anti-CRISPR Protein.
Stone NP, Hilbert BJ, Hidalgo D, Halloran KT, Lee J, Sontheimer EJ, Kelch BA.
Stone NP, et al.
Structure. 2018 Jul 3;26(7):936-947.e3. doi: 10.1016/j.str.2018.04.008. Epub 2018 May 17.
Structure. 2018.
PMID: 29779790
Free PMC article.
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The large terminase DNA packaging motor grips DNA with its ATPase domain for cleavage by the flexible nuclease domain.
Hilbert BJ, Hayes JA, Stone NP, Xu RG, Kelch BA.
Hilbert BJ, et al. Among authors: stone np.
Nucleic Acids Res. 2017 Apr 7;45(6):3591-3605. doi: 10.1093/nar/gkw1356.
Nucleic Acids Res. 2017.
PMID: 28082398
Free PMC article.
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