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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1994 1
1995 1
1996 1
1997 4
1998 2
1999 2
2000 1
2001 5
2002 2
2003 5
2005 7
2006 6
2007 7
2008 8
2009 9
2010 9
2011 14
2012 6
2013 8
2014 9
2015 5
2016 5
2017 9
2018 11
2019 11
2020 7
2021 7
2022 8
2023 2
2024 4

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158 results

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Page 1
Discovery of an Orally Bioavailable and Selective PKMYT1 Inhibitor, RP-6306.
Szychowski J, Papp R, Dietrich E, Liu B, Vallée F, Leclaire ME, Fourtounis J, Martino G, Perryman AL, Pau V, Yin SY, Mader P, Roulston A, Truchon JF, Marshall CG, Diallo M, Duffy NM, Stocco R, Godbout C, Bonneau-Fortin A, Kryczka R, Bhaskaran V, Mao D, Orlicky S, Beaulieu P, Turcotte P, Kurinov I, Sicheri F, Mamane Y, Gallant M, Black WC. Szychowski J, et al. Among authors: sicheri f. J Med Chem. 2022 Aug 11;65(15):10251-10284. doi: 10.1021/acs.jmedchem.2c00552. Epub 2022 Jul 26. J Med Chem. 2022. PMID: 35880755 Free PMC article.
Identification of RP-6685, an Orally Bioavailable Compound that Inhibits the DNA Polymerase Activity of Polθ.
Bubenik M, Mader P, Mochirian P, Vallée F, Clark J, Truchon JF, Perryman AL, Pau V, Kurinov I, Zahn KE, Leclaire ME, Papp R, Mathieu MC, Hamel M, Duffy NM, Godbout C, Casas-Selves M, Falgueyret JP, Baruah PS, Nicolas O, Stocco R, Poirier H, Martino G, Fortin AB, Roulston A, Chefson A, Dorich S, St-Onge M, Patel P, Pellerin C, Ciblat S, Pinter T, Barabé F, El Bakkouri M, Parikh P, Gervais C, Sfeir A, Mamane Y, Morris SJ, Black WC, Sicheri F, Gallant M. Bubenik M, et al. Among authors: sicheri f. J Med Chem. 2022 Oct 13;65(19):13198-13215. doi: 10.1021/acs.jmedchem.2c00998. Epub 2022 Sep 20. J Med Chem. 2022. PMID: 36126059 Free PMC article.
Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer.
Zhao N, Cao J, Xu L, Tang Q, Dobrolecki LE, Lv X, Talukdar M, Lu Y, Wang X, Hu DZ, Shi Q, Xiang Y, Wang Y, Liu X, Bu W, Jiang Y, Li M, Gong Y, Sun Z, Ying H, Yuan B, Lin X, Feng XH, Hartig SM, Li F, Shen H, Chen Y, Han L, Zeng Q, Patterson JB, Kaipparettu BA, Putluri N, Sicheri F, Rosen JM, Lewis MT, Chen X. Zhao N, et al. Among authors: sicheri f. J Clin Invest. 2018 Apr 2;128(4):1283-1299. doi: 10.1172/JCI95873. Epub 2018 Feb 26. J Clin Invest. 2018. PMID: 29480818 Free PMC article.
High Accuracy Prediction of PROTAC Complex Structures.
Ignatov M, Jindal A, Kotelnikov S, Beglov D, Posternak G, Tang X, Maisonneuve P, Poda G, Batey RA, Sicheri F, Whitty A, Tonge PJ, Vajda S, Kozakov D. Ignatov M, et al. Among authors: sicheri f. J Am Chem Soc. 2023 Apr 5;145(13):7123-7135. doi: 10.1021/jacs.2c09387. Epub 2023 Mar 24. J Am Chem Soc. 2023. PMID: 36961978 Free PMC article.
Remembering a pioneer in biotechnology.
Aviv T, Sicheri F, Bernstein A, Weinberg RA. Aviv T, et al. Among authors: sicheri f. Nature. 2021 Dec;600(7889):386. doi: 10.1038/d41586-021-03696-9. Nature. 2021. PMID: 34907398 No abstract available.
The structural and functional workings of KEOPS.
Beenstock J, Sicheri F. Beenstock J, et al. Among authors: sicheri f. Nucleic Acids Res. 2021 Nov 8;49(19):10818-10834. doi: 10.1093/nar/gkab865. Nucleic Acids Res. 2021. PMID: 34614169 Free PMC article. Review.
Engineered SH2 Domains for Targeted Phosphoproteomics.
Martyn GD, Veggiani G, Kusebauch U, Morrone SR, Yates BP, Singer AU, Tong J, Manczyk N, Gish G, Sun Z, Kurinov I, Sicheri F, Moran MF, Moritz RL, Sidhu SS. Martyn GD, et al. Among authors: sicheri f. ACS Chem Biol. 2022 Jun 17;17(6):1472-1484. doi: 10.1021/acschembio.2c00051. Epub 2022 May 25. ACS Chem Biol. 2022. PMID: 35613471 Free PMC article.
Dimerization-induced allostery in protein kinase regulation.
Lavoie H, Li JJ, Thevakumaran N, Therrien M, Sicheri F. Lavoie H, et al. Among authors: sicheri f. Trends Biochem Sci. 2014 Oct;39(10):475-86. doi: 10.1016/j.tibs.2014.08.004. Epub 2014 Sep 11. Trends Biochem Sci. 2014. PMID: 25220378 Review.
158 results