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Mutation effects predicted from sequence co-variation.
Hopf TA, Ingraham JB, Poelwijk FJ, Schärfe CP, Springer M, Sander C, Marks DS. Hopf TA, et al. Among authors: scharfe cp. Nat Biotechnol. 2017 Feb;35(2):128-135. doi: 10.1038/nbt.3769. Epub 2017 Jan 16. Nat Biotechnol. 2017. PMID: 28092658 Free PMC article.
Genetic variation in human drug-related genes.
Schärfe CPI, Tremmel R, Schwab M, Kohlbacher O, Marks DS. Schärfe CPI, et al. Genome Med. 2017 Dec 22;9(1):117. doi: 10.1186/s13073-017-0502-5. Genome Med. 2017. PMID: 29273096 Free PMC article.
The EVcouplings Python framework for coevolutionary sequence analysis.
Hopf TA, Green AG, Schubert B, Mersmann S, Schärfe CPI, Ingraham JB, Toth-Petroczy A, Brock K, Riesselman AJ, Palmedo P, Kang C, Sheridan R, Draizen EJ, Dallago C, Sander C, Marks DS. Hopf TA, et al. Among authors: scharfe cpi. Bioinformatics. 2019 May 1;35(9):1582-1584. doi: 10.1093/bioinformatics/bty862. Bioinformatics. 2019. PMID: 30304492 Free PMC article.
ClinVAP: a reporting strategy from variants to therapeutic options.
Sürün B, Schärfe CPI, Divine MR, Heinrich J, Toussaint NC, Zimmermann L, Beha J, Kohlbacher O. Sürün B, et al. Among authors: scharfe cpi. Bioinformatics. 2020 Apr 1;36(7):2316-2317. doi: 10.1093/bioinformatics/btz924. Bioinformatics. 2020. PMID: 31830259 Free PMC article.