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Page 1
High GC content causes orphan proteins to be intrinsically disordered.
PLoS Comput Biol. 2017 Mar 29;13(3):e1005375. doi: 10.1371/journal.pcbi.1005375. eCollection 2017 Mar.
PLoS Comput Biol. 2017.
PMID: 28355220
Free PMC article.
Protein expansion is primarily due to indels in intrinsically disordered regions.
Light S, Sagit R, Sachenkova O, Ekman D, Elofsson A.
Light S, et al. Among authors: sachenkova o.
Mol Biol Evol. 2013 Dec;30(12):2645-53. doi: 10.1093/molbev/mst157. Epub 2013 Sep 12.
Mol Biol Evol. 2013.
PMID: 24037790
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A New Census of Protein Tandem Repeats and Their Relationship with Intrinsic Disorder.
Delucchi M, Schaper E, Sachenkova O, Elofsson A, Anisimova M.
Delucchi M, et al. Among authors: sachenkova o.
Genes (Basel). 2020 Apr 9;11(4):407. doi: 10.3390/genes11040407.
Genes (Basel). 2020.
PMID: 32283633
Free PMC article.
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A simple metric of promoter architecture robustly predicts expression breadth of human genes suggesting that most transcription factors are positive regulators.
Hurst LD, Sachenkova O, Daub C, Forrest AR, Huminiecki L; FANTOM consortium.
Hurst LD, et al. Among authors: sachenkova o.
Genome Biol. 2014 Jul 31;15(7):413. doi: 10.1186/s13059-014-0413-3.
Genome Biol. 2014.
PMID: 25079787
Free PMC article.
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