Markegard E[au] - Search Results

Year	Number of Results
2011	1
2012	1
2013	1
2016	1
2017	1
2018	1
2020	1
2024	0

1

Dual gene activation and knockout screen reveals directional dependencies in genetic networks.

Boettcher M, Tian R, Blau JA, Markegard E, Wagner RT, Wu D, Mo X, Biton A, Zaitlen N, Fu H, McCormick F, Kampmann M, McManus MT. Boettcher M, et al. Among authors: markegard e. Nat Biotechnol. 2018 Feb;36(2):170-178. doi: 10.1038/nbt.4062. Epub 2018 Jan 15. Nat Biotechnol. 2018. PMID: 29334369 Free PMC article.

2

Structural Insights into the SPRED1-Neurofibromin-KRAS Complex and Disruption of SPRED1-Neurofibromin Interaction by Oncogenic EGFR.

Yan W, Markegard E, Dharmaiah S, Urisman A, Drew M, Esposito D, Scheffzek K, Nissley DV, McCormick F, Simanshu DK. Yan W, et al. Among authors: markegard e. Cell Rep. 2020 Jul 21;32(3):107909. doi: 10.1016/j.celrep.2020.107909. Cell Rep. 2020. PMID: 32697994 Free PMC article.

3

Tonic LAT-HDAC7 Signals Sustain Nur77 and Irf4 Expression to Tune Naive CD4 T Cells.

Myers DR, Lau T, Markegard E, Lim HW, Kasler H, Zhu M, Barczak A, Huizar JP, Zikherman J, Erle DJ, Zhang W, Verdin E, Roose JP. Myers DR, et al. Among authors: markegard e. Cell Rep. 2017 May 23;19(8):1558-1571. doi: 10.1016/j.celrep.2017.04.076. Cell Rep. 2017. PMID: 28538176 Free PMC article.

4

Basal LAT-diacylglycerol-RasGRP1 signals in T cells maintain TCRα gene expression.

Markegard E, Trager E, Yang CW, Zhang W, Weiss A, Roose JP. Markegard E, et al. PLoS One. 2011;6(9):e25540. doi: 10.1371/journal.pone.0025540. Epub 2011 Sep 26. PLoS One. 2011. PMID: 21966541 Free PMC article.

5

A phospholipase C-γ1-independent, RasGRP1-ERK-dependent pathway drives lymphoproliferative disease in linker for activation of T cells-Y136F mutant mice.

Kortum RL, Rouquette-Jazdanian AK, Miyaji M, Merrill RK, Markegard E, Pinski JM, Wesselink A, Nath NN, Alexander CP, Li W, Kedei N, Roose JP, Blumberg PM, Samelson LE, Sommers CL. Kortum RL, et al. Among authors: markegard e. J Immunol. 2013 Jan 1;190(1):147-58. doi: 10.4049/jimmunol.1201458. Epub 2012 Dec 3. J Immunol. 2013. PMID: 23209318 Free PMC article.

6

Preclinical efficacy of a RAF inhibitor that evades paradoxical MAPK pathway activation in protein kinase BRAF-mutant lung cancer.

Okimoto RA, Lin L, Olivas V, Chan E, Markegard E, Rymar A, Neel D, Chen X, Hemmati G, Bollag G, Bivona TG. Okimoto RA, et al. Among authors: markegard e. Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):13456-13461. doi: 10.1073/pnas.1610456113. Epub 2016 Nov 9. Proc Natl Acad Sci U S A. 2016. PMID: 27834212 Free PMC article.

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