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Page 1
Bi-allelic Loss of CDKN2A Initiates Melanoma Invasion via BRN2 Activation.
Zeng H, Jorapur A, Shain AH, Lang UE, Torres R, Zhang Y, McNeal AS, Botton T, Lin J, Donne M, Bastian IN, Yu R, North JP, Pincus L, Ruben BS, Joseph NM, Yeh I, Bastian BC, Judson RL. Zeng H, et al. Among authors: jorapur a. Cancer Cell. 2018 Jul 9;34(1):56-68.e9. doi: 10.1016/j.ccell.2018.05.014. Cancer Cell. 2018. PMID: 29990501 Free PMC article.
EPHB4 is a therapeutic target in AML and promotes leukemia cell survival via AKT.
Merchant AA, Jorapur A, McManus A, Liu R, Krasnoperov V, Chaudhry P, Singh M, Harton L, Agajanian M, Kim M, Triche TJ Jr, Druker BJ, Tyner JW, Gill PS. Merchant AA, et al. Among authors: jorapur a. Blood Adv. 2017 Aug 28;1(20):1635-1644. doi: 10.1182/bloodadvances.2017005694. eCollection 2017 Sep 12. Blood Adv. 2017. PMID: 29296810 Free PMC article.
Deciphering intratumoral heterogeneity using integrated clonal tracking and single-cell transcriptome analyses.
Contreras-Trujillo H, Eerdeng J, Akre S, Jiang D, Contreras J, Gala B, Vergel-Rodriguez MC, Lee Y, Jorapur A, Andreasian A, Harton L, Bramlett CS, Nogalska A, Xiao G, Lee JW, Chan LN, Müschen M, Merchant AA, Lu R. Contreras-Trujillo H, et al. Among authors: jorapur a. Nat Commun. 2021 Nov 11;12(1):6522. doi: 10.1038/s41467-021-26771-1. Nat Commun. 2021. PMID: 34764253 Free PMC article.
The genomic landscapes of individual melanocytes from human skin.
Tang J, Fewings E, Chang D, Zeng H, Liu S, Jorapur A, Belote RL, McNeal AS, Tan TM, Yeh I, Arron ST, Judson-Torres RL, Bastian BC, Shain AH. Tang J, et al. Among authors: jorapur a. Nature. 2020 Oct;586(7830):600-605. doi: 10.1038/s41586-020-2785-8. Epub 2020 Oct 7. Nature. 2020. PMID: 33029006 Free PMC article.
EBV+ tumors exploit tumor cell-intrinsic and -extrinsic mechanisms to produce regulatory T cell-recruiting chemokines CCL17 and CCL22.
Jorapur A, Marshall LA, Jacobson S, Xu M, Marubayashi S, Zibinsky M, Hu DX, Robles O, Jackson JJ, Baloche V, Busson P, Wustrow D, Brockstedt DG, Talay O, Kassner PD, Cutler G. Jorapur A, et al. PLoS Pathog. 2022 Jan 13;18(1):e1010200. doi: 10.1371/journal.ppat.1010200. eCollection 2022 Jan. PLoS Pathog. 2022. PMID: 35025968 Free PMC article.
Tumors establish resistance to immunotherapy by regulating Treg recruitment via CCR4.
Marshall LA, Marubayashi S, Jorapur A, Jacobson S, Zibinsky M, Robles O, Hu DX, Jackson JJ, Pookot D, Sanchez J, Brovarney M, Wadsworth A, Chian D, Wustrow D, Kassner PD, Cutler G, Wong B, Brockstedt DG, Talay O. Marshall LA, et al. Among authors: jorapur a. J Immunother Cancer. 2020 Nov;8(2):e000764. doi: 10.1136/jitc-2020-000764. J Immunother Cancer. 2020. PMID: 33243932 Free PMC article.