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A novel FADS2 isoform identified in human milk fat globule suppresses FADS2 mediated Δ6-desaturation of omega-3 fatty acids.
Kothapalli KSD, Park HG, Guo X, Sun X, Zou J, Hyon SS, Qin X, Lawrence P, Ran-Ressler RR, Zhang JY, Gu Z, Brenna JT. Kothapalli KSD, et al. Among authors: hyon ss. Prostaglandins Leukot Essent Fatty Acids. 2018 Nov;138:52-59. doi: 10.1016/j.plefa.2018.06.004. Epub 2018 Jun 28. Prostaglandins Leukot Essent Fatty Acids. 2018. PMID: 30041907 Free PMC article.
Positive Selection on a Regulatory Insertion-Deletion Polymorphism in FADS2 Influences Apparent Endogenous Synthesis of Arachidonic Acid.
Kothapalli KS, Ye K, Gadgil MS, Carlson SE, O'Brien KO, Zhang JY, Park HG, Ojukwu K, Zou J, Hyon SS, Joshi KS, Gu Z, Keinan A, Brenna JT. Kothapalli KS, et al. Among authors: hyon ss. Mol Biol Evol. 2016 Jul;33(7):1726-39. doi: 10.1093/molbev/msw049. Epub 2016 Mar 29. Mol Biol Evol. 2016. PMID: 27188529 Free PMC article.