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Year Number of Results
1998 1
1999 1
2007 3
2009 1
2010 3
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2012 4
2013 3
2014 5
2016 2
2017 7
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2019 8
2020 6
2021 5
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2023 7
2024 5

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68 results

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Page 1
3D cell culture models: Drug pharmacokinetics, safety assessment, and regulatory consideration.
Wang H, Brown PC, Chow ECY, Ewart L, Ferguson SS, Fitzpatrick S, Freedman BS, Guo GL, Hedrich W, Heyward S, Hickman J, Isoherranen N, Li AP, Liu Q, Mumenthaler SM, Polli J, Proctor WR, Ribeiro A, Wang JY, Wange RL, Huang SM. Wang H, et al. Among authors: ewart l. Clin Transl Sci. 2021 Sep;14(5):1659-1680. doi: 10.1111/cts.13066. Epub 2021 Jun 16. Clin Transl Sci. 2021. PMID: 33982436 Free PMC article. Review.
Reproducing human and cross-species drug toxicities using a Liver-Chip.
Jang KJ, Otieno MA, Ronxhi J, Lim HK, Ewart L, Kodella KR, Petropolis DB, Kulkarni G, Rubins JE, Conegliano D, Nawroth J, Simic D, Lam W, Singer M, Barale E, Singh B, Sonee M, Streeter AJ, Manthey C, Jones B, Srivastava A, Andersson LC, Williams D, Park H, Barrile R, Sliz J, Herland A, Haney S, Karalis K, Ingber DE, Hamilton GA. Jang KJ, et al. Among authors: ewart l. Sci Transl Med. 2019 Nov 6;11(517):eaax5516. doi: 10.1126/scitranslmed.aax5516. Sci Transl Med. 2019. PMID: 31694927
Advancing nonclinical innovation and safety in pharmaceutical testing.
Baker EJ, Beck NA, Berg EL, Clayton-Jeter HD, Chandrasekera PC, Curley JL, Donzanti BA, Ewart LC, Gunther JM, Kenna JG, LeCluyse EL, Liebman MN, Pugh CL, Watkins PB, Sullivan KM. Baker EJ, et al. Among authors: ewart lc. Drug Discov Today. 2019 Feb;24(2):624-628. doi: 10.1016/j.drudis.2018.11.011. Epub 2018 Nov 20. Drug Discov Today. 2019. PMID: 30468877 Free article. Review.
Performance assessment and economic analysis of a human Liver-Chip for predictive toxicology.
Ewart L, Apostolou A, Briggs SA, Carman CV, Chaff JT, Heng AR, Jadalannagari S, Janardhanan J, Jang KJ, Joshipura SR, Kadam MM, Kanellias M, Kujala VJ, Kulkarni G, Le CY, Lucchesi C, Manatakis DV, Maniar KK, Quinn ME, Ravan JS, Rizos AC, Sauld JFK, Sliz JD, Tien-Street W, Trinidad DR, Velez J, Wendell M, Irrechukwu O, Mahalingaiah PK, Ingber DE, Scannell JW, Levner D. Ewart L, et al. Commun Med (Lond). 2022 Dec 6;2(1):154. doi: 10.1038/s43856-022-00209-1. Commun Med (Lond). 2022. PMID: 36473994 Free PMC article.
Application of Microphysiological Systems to Enhance Safety Assessment in Drug Discovery.
Ewart L, Dehne EM, Fabre K, Gibbs S, Hickman J, Hornberg E, Ingelman-Sundberg M, Jang KJ, Jones DR, Lauschke VM, Marx U, Mettetal JT, Pointon A, Williams D, Zimmermann WH, Newham P. Ewart L, et al. Annu Rev Pharmacol Toxicol. 2018 Jan 6;58:65-82. doi: 10.1146/annurev-pharmtox-010617-052722. Epub 2017 Oct 13. Annu Rev Pharmacol Toxicol. 2018. PMID: 29029591 Review.
68 results