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Systems modelling ageing: from single senescent cells to simple multi-cellular models.
Martinez Guimera A, Welsh C, Dalle Pezze P, Fullard N, Nelson G, Roger MF, Przyborski SA, Shanley DP. Martinez Guimera A, et al. Among authors: dalle pezze p. Essays Biochem. 2017 Jul 11;61(3):369-377. doi: 10.1042/EBC20160087. Print 2017 Jul 15. Essays Biochem. 2017. PMID: 28698310 Free PMC article. Review.
The systems biology format converter.
Rodriguez N, Pettit JB, Dalle Pezze P, Li L, Henry A, van Iersel MP, Jalowicki G, Kutmon M, Natarajan KN, Tolnay D, Stefan MI, Evelo CT, Le Novère N. Rodriguez N, et al. Among authors: dalle pezze p. BMC Bioinformatics. 2016 Apr 5;17:154. doi: 10.1186/s12859-016-1000-2. BMC Bioinformatics. 2016. PMID: 27044654 Free PMC article.
A systems study reveals concurrent activation of AMPK and mTOR by amino acids.
Dalle Pezze P, Ruf S, Sonntag AG, Langelaar-Makkinje M, Hall P, Heberle AM, Razquin Navas P, van Eunen K, Tölle RC, Schwarz JJ, Wiese H, Warscheid B, Deitersen J, Stork B, Fäßler E, Schäuble S, Hahn U, Horvatovich P, Shanley DP, Thedieck K. Dalle Pezze P, et al. Nat Commun. 2016 Nov 21;7:13254. doi: 10.1038/ncomms13254. Nat Commun. 2016. PMID: 27869123 Free PMC article.
Increasing extracellular H2O2 produces a bi-phasic response in intracellular H2O2, with peroxiredoxin hyperoxidation only triggered once the cellular H2O2-buffering capacity is overwhelmed.
Tomalin LE, Day AM, Underwood ZE, Smith GR, Dalle Pezze P, Rallis C, Patel W, Dickinson BC, Bähler J, Brewer TF, Chang CJ, Shanley DP, Veal EA. Tomalin LE, et al. Among authors: dalle pezze p. Free Radic Biol Med. 2016 Jun;95:333-48. doi: 10.1016/j.freeradbiomed.2016.02.035. Epub 2016 Mar 2. Free Radic Biol Med. 2016. PMID: 26944189 Free PMC article.