CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer

Nat Genet. 2017 Jan 31;49(2):170-174. doi: 10.1038/ng.3774.

Abstract

CIViC is an expert-crowdsourced knowledgebase for Clinical Interpretation of Variants in Cancer describing the therapeutic, prognostic, diagnostic and predisposing relevance of inherited and somatic variants of all types. CIViC is committed to open-source code, open-access content, public application programming interfaces (APIs) and provenance of supporting evidence to allow for the transparent creation of current and accurate variant interpretations for use in cancer precision medicine.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Crowdsourcing / methods*
  • Genetic Variation
  • Humans
  • Knowledge Bases*
  • Mutation
  • Neoplasms / etiology
  • Neoplasms / genetics*