TY - JOUR T1 - Network structural features affect stability of Calvin Bassham Benson (CBB) pathway in plants JF - bioRxiv DO - 10.1101/034637 SP - 034637 AU - Matthew K Theisen Y1 - 2016/01/01 UR - http://biorxiv.org/content/early/2016/01/04/034637.abstract N2 - The stability of the Calvin Bassham Benson cycle remains an area of active computational research. The potential impacts on our understanding of biology and the prospect for bioengineered plants with higher productivity may both be impacted by a greater understanding of this area. Here we use the ensemble modelling robustness analysis (EMRA) framework to show that the action of the phosphate/G3P antiporter is much more significant for maintenance of stability of a recently proposed G6P shunt. Additionally, we interpret recent results suggesting that overexpression of RuBiSCO does not improve growth rate of plants but overexpression of SBPase does. Our simulations reproduce this result, but only in models which do not include the G6P shunt. Taken together, these results may suggest a situational role for the G6P shunt, possibly in dynamic situations under starvation or other stress conditions. ER -