RT Journal Article
SR Electronic
T1 Incoherent feedforward motifs as immune change detectors
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 035600
DO 10.1101/035600
A1 Eduardo D. Sontag
YR 2015
UL http://biorxiv.org/content/early/2015/12/30/035600.abstract
AB We speculate that incoherent feedforward loops may be phenomenologically involved in self/nonself discrimination in immune-infection and immune-tumor interactions, acting as “change detectors”. In turn, this may result in logarithmic sensing (Weber phenomenon) and even scale invariance (fold-change detection).