RT Journal Article
SR Electronic
T1 solarius: an R interface to SOLAR for variance component analysis in pedigrees
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 035378
DO 10.1101/035378
A1 Andrey Ziyatdinov
A1 Helena Brunel
A1 Angel Martinez-Perez
A1 Alfonso Buil
A1 Alexandre Perera
A1 Jose Manuel Soria
YR 2015
UL http://biorxiv.org/content/early/2015/12/25/035378.abstract
AB Summary The open source environment R is one of the most widely used software for statistical computing. It provides a variety of applications including statistical genetics. Most of the powerful tools for quantitative genetic analyses are stand-alone free programs developed by researchers in academia. SOLAR is the standard software program to perform linkage and association mappings of the quantitative trait loci (QTLs) in pedigrees of arbitrary size and complexity. solarius allows the user to exploit the variance component methods implemented in SOLAR. It automates such routine operations as formatting pedigree and phenotype data. It also parses the model output and contains summary and plotting functions for exploration of the results. In addition, solarius enables parallel computing of the linkage and association analyses, that makes the calculation of genome-wide scans more efficient.Availability and implementation solarius is available on CRAN https://cran.r-project.org/package=solarius and on GitHub https://github.com/ugcd/solarius. See http://solar.txbiomedgenetics.org/ for more information about SOLAR.Contact aziyatdinov{at}santpau.cat