RT Journal Article
SR Electronic
T1 Activity sources from fast large-scale brain recordings in adult Drosophila
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 033803
DO 10.1101/033803
A1 Sophie Aimon
A1 Takeo Katsuki
A1 Logan Grosenick
A1 Michael Broxton
A1 Karl Deisseroth
A1 Ralph Greenspan
YR 2015
UL http://biorxiv.org/content/early/2015/12/10/033803.abstract
AB We provide a method to record near-whole brain activity in behaving adult flies and extract signals from specific anatomical structures. We image pan-neuronal calcium or voltage sensors fluorescence at high speed with light field microscopy. We then apply computational methods to extract functional maps, and find that their characteristic shape match the anatomy of sub-neuropile regions and sometimes small population of neurons. Associated time series are also consistent with the literature.