PT  - JOURNAL ARTICLE
AU  - Sophie Aimon
AU  - Takeo Katsuki
AU  - Logan Grosenick
AU  - Michael Broxton
AU  - Karl Deisseroth
AU  - Ralph Greenspan
TI  - Activity sources from fast large-scale brain recordings in adult Drosophila
AID  - 10.1101/033803
DP  - 2015 Jan 01
TA  - bioRxiv
PG  - 033803
4099  - http://biorxiv.org/content/early/2015/12/10/033803.short
4100  - http://biorxiv.org/content/early/2015/12/10/033803.full
AB  - We provide a method to record near-whole brain activity in behaving adult flies and extract signals from specific anatomical structures. We image pan-neuronal calcium or voltage sensors fluorescence at high speed with light field microscopy. We then apply computational methods to extract functional maps, and find that their characteristic shape match the anatomy of sub-neuropile regions and sometimes small population of neurons. Associated time series are also consistent with the literature.