TY - JOUR T1 - Physics-based multiscale mass transport model in drug delivery and tumor microenvironment JF - bioRxiv DO - 10.1101/031252 SP - 031252 AU - Arturas Ziemys AU - Milos Kojic AU - Mauro Ferrari Y1 - 2015/01/01 UR - http://biorxiv.org/content/early/2015/11/10/031252.abstract N2 - We describe multiscale transport model, which was developed to simulate drug diffusion and convection in tissues and drug vectors. Models rely on material properties and physical laws of transport. Our methods show that drug transport analysis may provide deep insight into mechanisms of pharmacokinetics useful in nanotherapeutics and transport study within tumor microenvironment. Because the method relies on material properties and structures, the approach can help studying phenotypical differences as well. ER -