TY - JOUR T1 - Multi-Unit Activity contains information about spatial stimulus structure in mouse primary visual cortex JF - bioRxiv DO - 10.1101/029108 SP - 029108 AU - Marie Tolkiehn AU - Simon R. Schultz Y1 - 2015/01/01 UR - http://biorxiv.org/content/early/2015/10/14/029108.abstract N2 - This study investigates the spatial and directional tuning of Multi-Unit Activity (MUA) in mouse primary visual cortex and how MUA can reflect spatiotemporal structures contained in moving gratings. Analysis of multi-shank laminar electrophysiological recordings from mouse primary visual cortex indicates a directional preference for moving gratings around 180°, while preferred spatial frequency peaks around 0.02 cycles per degree, which is similar as reported in single-unit studies. Using only features from MUA, we further achieved a significant performance in decoding spatial frequency or direction of moving gratings, with average decoding performances of up to 58.54% for 8 directions, and 44% correctly identified spatial frequencies against chance level of 16.7%. ER -