TY - JOUR T1 - The UCSC Genome Browser database: 2016 update JF - bioRxiv DO - 10.1101/027037 SP - 027037 AU - Matthew L. Speir AU - Ann S. Zweig AU - Kate R. Rosenbloom AU - Brian J. Raney AU - Benedict Paten AU - Parisa Nejad AU - Brian T. Lee AU - Katrina Learned AU - Donna Karolchik AU - Angie S. Hinrichs AU - Steve Heitner AU - Rachel A. Harte AU - Maximilian Haeussler AU - Luvina Guruvadoo AU - Pauline A. Fujita AU - Christopher Eisenhart AU - Mark Diekhans AU - Hiram Clawson AU - Jonathan Casper AU - Galt P. Barber AU - David Haussler AU - Robert M. Kuhn AU - W. James Kent Y1 - 2015/01/01 UR - http://biorxiv.org/content/early/2015/09/17/027037.abstract N2 - For the past 15 years, the UCSC Genome Browser (http://genome.ucsc.edu/) has served the international research community by offering an integrated platform for viewing and analyzing information from a large database of genome assemblies and their associated annotations. The UCSC Genome Browser has been under continuous development since its inception with new data sets and software features added frequently. Some release highlights of this year include new and updated genome browsers for various assemblies, including bonobo and zebrafish; new gene annotation sets; improvements to track and assembly hub support; and a new interactive tool, the “Data Integrator”, for intersecting data from multiple tracks. We have greatly expanded the data sets available on the most recent human assembly, hg38/GRCh38, to include updated gene prediction sets from GENCODE, more phenotype- and disease-associated variants from ClinVar and ClinGen, more genomic regulatory data, and a new multiple genome alignment. ER -