TY - JOUR T1 - Selection on heritable heterozygosity but no response to selection. Why? JF - bioRxiv DO - 10.1101/026492 SP - 026492 AU - Tim Coulson AU - Sonya Clegg Y1 - 2015/01/01 UR - http://biorxiv.org/content/early/2015/09/09/026492.abstract N2 - The realisation that heterozygosity can be heritable has recently generated some elegant research. However, none of this work has discussed the fact that when heterozygote advantage occurs, heterozygosity can be heritable, yet allele frequencies remain at equilibrium and do not evolve with time. From a quantitative genetic perspective this means the character is heritable, is under selection, yet no response to selection is observed. We explain why this is the case, and discuss potential implications for the study of evolution in the wild. ER -