RT Journal Article
SR Electronic
T1 TreeQTL: hierarchical error control for eQTL findings
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 021170
DO 10.1101/021170
A1 Christine Peterson
A1 Marina Bogomolov
A1 Yoav Benjamini
A1 Chiara Sabatti
YR 2015
UL http://biorxiv.org/content/early/2015/07/07/021170.abstract
AB Summary Commonly used multiplicity adjustments fail to control the error rate for reported findings in many expression quantitative trait loci (eQTL) studies. TreeQTL implements a stage-wise multiple testing procedure which allows control of appropriate error rates defined relative to a hierarchical grouping of the eQTL hypotheses.Availability and Implementation The R package TreeQTL is available for download at http://bioinformatics.org/treeqtl.Contact sabatti{at}stanford.edu